SCHEMBL30719583

SCHEMBL30719583

COc1cccc(Nc2nc(Cl)nc3[nH]cnc23)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.54
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
GRM4 Q14833 1/20 0.48
SYK P43405 1/20 0.47
SRC P12931 2/20 0.47
EGFR P00533 3/20 0.46
ERBB3 P21860 1/20 0.46
KDR P35968 2/20 0.46
PDGFRB P09619 1/20 0.46
LRRK2 Q5S007 2/20 0.45
DYRK3 O43781 1/20 0.45
MAP4K4 O95819 1/20 0.45
PDGFRA P16234 1/20 0.45
LTK P29376 1/20 0.45
GRK5 P34947 1/20 0.45
MAPK8 P45983 1/20 0.45
CDK8 P49336 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3004036 1.00 NPC1 (0.54) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL3010051 0.89 SMN1; SMN2 (0.45) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL24862147 0.88 BRAF (0.40) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL2998386 0.86 NPC1 (0.55) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL2991717 0.85 HTT (0.54) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL29355778 0.85 HTT (0.54) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL3006445 0.85 EGFR (0.56) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL30162946 0.85 EGFR (0.56) NPC1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL3000771 0.85 MAPT (0.52) NPC1RAB9ASMN1; SMN2SYKSRC
SCHEMBL3001568 0.83 BRAF (0.53) GRM4SYKEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120035584-A Substituted N-phenyluracils and salts thereof and their use as herbicidal agents 拜耳公司 2025-05-23 CN disclosed
WO-2025103939-A1 SULFONIMIDOYL BENZAMIDES WITH HERBICIDAL ACTION BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
WO-2025103927-A1 SUBSTITUTED OXYIMINOMETHYLPHENYL URACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
WO-2025103931-A1 SUBSTITUTED CYCLOPROPYLOXYPHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
WO-2025103929-A1 SUBSTITUTED N-BENZOIC ACID URACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
WO-2024104954-A1 SUBSTITUTED CYCLOALKYLOXYPHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-05-23 WO disclosed
WO-2024015949-A2 METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE MONSANTO TECHNOLOGY LLC (US) 2024-01-18 WO disclosed