SCHEMBL29356089

SCHEMBL29356089

Cc1nnc(Cl)c(-c2c(F)cc(F)cc2F)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
HPGD P15428 4/20 0.35
KMT2A Q03164 3/20 0.35
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 4/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
BRD4 O60885 2/20 0.33
CHEK1 O14757 1/20 0.33
AKT2 P31751 1/20 0.33
BRD2 P25440 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2347918 1.00 MAOB (0.40) MAOBNPC1RAB9AHPGDKMT2A
SCHEMBL14962991 0.91 MAOB (0.40) MAOBHPGDKMT2ALMNAL3MBTL1
SCHEMBL2354401 0.89 MEN1 (0.35) NPC1RAB9AKMT2AMEN1CYP1A2
SCHEMBL13165373 0.89 MAOB (0.45) MAOBNPC1RAB9AKMT2AL3MBTL1
SCHEMBL3334324 0.88 DHODH (0.37) MAOBCYP1A2CYP2C9
SCHEMBL3336063 0.88 KMT2A (0.37) MAOBHPGDKMT2ALMNAL3MBTL1
SCHEMBL1869939 0.88 RAB9A (0.36) NPC1RAB9AKMT2ALMNAMAPT
SCHEMBL1873945 0.88 KMT2A (0.34) NPC1RAB9AHPGDKMT2ALMNA
SCHEMBL10015953 0.88 MAOB (0.42) MAOBHPGDKMT2ALMNAL3MBTL1
SCHEMBL2350675 0.87 IKBKE (0.40) NPC1RAB9AKMT2AMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
EP-4422402-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
CN-118368985-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-19 CN claimed
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 CN claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 CN claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 CN claimed
WO-2023072784-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
WO-2023072785-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
EP-4747241-A1 BENZIMIDAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-05-27 EP disclosed
EP-4717089-A2 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-04-01 EP disclosed
EP-4695246-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4694686-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695244-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695253-A1 IMIDAZO BICYCLIC DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
EP-3953343-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
CN-113979962-A Fungicidal compositions 先正达参股股份有限公司 2022-01-28 CN disclosed
WO-2022017975-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-01-27 WO disclosed
EP-3941898-A1 FUNGICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-01-26 EP disclosed
CN-113966171-A Fungicidal compositions 先正达农作物保护股份公司 2022-01-21 CN disclosed