Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22470075 | 1.00 | KCNN4 (0.45) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL28647448 | 1.00 | KCNN4 (0.45) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL28648705 | 0.94 | KCNN4 (0.49) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL28648709 | 0.94 | KCNN4 (0.49) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL28648706 | 0.94 | KCNN4 (0.49) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL29261962 | 0.88 | IL1B (0.42) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL29261963 | 0.88 | IL1B (0.42) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL29355246 | 0.88 | IL1B (0.42) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL22470110 | 0.87 | KCNN4 (0.43) | KCNN4APPHTR1AADRA2ADRD2 | |
| SCHEMBL29356640 | 0.87 | KCNN4 (0.43) | KCNN4APPHTR1AADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941903-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Saniona A/S (DK) | 2022-01-26 | — | — | EP | disclosed |