Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 20/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19208539 | 1.00 | CFD (1.00) | CFDCYP3A4 | |
| SCHEMBL19208427 | 1.00 | CFD (1.00) | CFDCYP3A4 | |
| SCHEMBL19208541 | 1.00 | CFD (1.00) | CFDCYP3A4 | |
| SCHEMBL29781925 | 1.00 | CFD (1.00) | CFDCYP3A4 | |
| SCHEMBL19208114 | 0.91 | CFD (1.00) | CFDCYP3A4 | |
| SCHEMBL19208116 | 0.91 | CFD (1.00) | CFDCYP3A4 | |
| SCHEMBL29782034 | 0.91 | CFD (1.00) | CFDCYP3A4 | |
| SCHEMBL19208696 | 0.83 | CFD (0.71) | CFDCYP3A4 | |
| SCHEMBL29781563 | 0.83 | CFD (0.71) | CFDCYP3A4 | |
| SCHEMBL19208695 | 0.83 | CFD (0.71) | CFDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490751-A | Factor D inhibitors | 拜奥克里斯特制药公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-109121414-B | Benzopyrazole compounds and analogs thereof | 拜奥克里斯特制药公司 | 2022-07-05 | — | — | CN | disclosed |
| EP-3411411-B3 | 1H-INDAZOLE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS FACTOR D INHIBITORS FOR TREATING DISEASES CHARACTERIZED BY ABERRANT COMPLEMENT SYSTEM ACTIVITY, SUCH AS E.G. IMMUNOLOGICAL DISORDERS | BIOCRYST PHARM INC (US) | 2022-01-26 | — | — | EP | disclosed |