Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Quinapril. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE known ✓ | P12821 | 16/20 | 0.98 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.98 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinapril SCHEMBL4359590 | 1.00 | ACE (0.98) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL29381792 | 1.00 | ACE (0.98) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL7421784 | 1.00 | ACE (0.98) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL41404 | 1.00 | ACE (0.98) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL153436 | 1.00 | ACE (0.98) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL6548496 | 1.00 | ACE (0.98) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL11294979 | 0.99 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL678447 | 0.99 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL13575806 | 0.99 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 | |
| Quinapril SCHEMBL11286555 | 0.99 | ACE (1.00) | ACEABCB11PDE3ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4491469-B1 | BRAKING SYSTEM FOR AT LEAST ONE VEHICLE, SYSTEM AND METHOD FOR CALIBRATING A BRAKING SYSTEM OF AT LEAST ONE VEHICLE, AND VEHICLE | FAIVELEY TRANSPORT ITALIA SPA (IT) | 2026-04-08 | — | — | EP | claimed |
| US-12360045-B2 | Light detecting device and light detecting method | NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) | 2025-07-15 | — | — | US | claimed |
| CN-111585585-B | Device and method for realizing Ping function of antenna | 普罗斯通信技术（苏州）有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-20250042376-A1 | BRAKING SYSTEM FOR AT LEAST ONE VEHICLE, SYSTEM AND PROCESS FOR THE CALIBRATION OF A BRAKING SYSTEM OF AT LEAST ONE VEHICLE, AND VEHICLE | FAIVELEY TRANSPORT ITALIA S.P.A. (IT) | 2025-02-06 | — | — | US | claimed |
| EP-4491469-A1 | BRAKING SYSTEM FOR AT LEAST ONE VEHICLE, SYSTEM AND METHOD FOR CALIBRATING A BRAKING SYSTEM OF AT LEAST ONE VEHICLE, AND VEHICLE | Faiveley Transport Italia S.p.A. (IT) | 2025-01-15 | — | — | EP | claimed |
| US-20240282425-A1 | AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS | LOW GORDON KEITH (US) | 2024-08-22 | — | — | US | claimed |
| CN-112584984-B | Auxiliary metrology position coordinate determination system for a robot including an alignment sensor | 株式会社三丰 | 2024-07-23 | — | — | CN | claimed |
| CN-114553883-B | Cloud edge end cooperative data acquisition and privacy protection method and system based on blockchain | 北京中科锐链科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| EP-4329195-A1 | SWITCHABLE FILTER | KMW Inc. (KR) | 2024-02-28 | — | — | EP | claimed |
| CN-117581477-A | Switchable filter | 株式会社KMW | 2024-02-20 | — | — | CN | claimed |
| CN-218275016-U | Switchable filter | 株式会社KMW | 2023-01-10 | — | — | CN | claimed |
| US-20220416415-A1 | WIRELESS TELECOMMUNICATION ANTENNA MOUNT AND CONTROL SYSTEM AND METHODS OF OPERATING THE SAME | RADIARC TECHNOLOGIES, LLC (US) | 2022-12-29 | — | — | US | claimed |
| CN-113940831-B | Intelligent nursing bed electric control system with voice control and vital sign monitoring functions | 青岛豪江智能科技股份有限公司 | 2022-12-16 | — | — | CN | claimed |
| US-11511496-B2 | Means of retaining a product in a receptacle | DOW SILICONES CORPORATION (US) | 2022-11-29 | — | — | US | claimed |
| WO-2022225294-A1 | SWITCHABLE FILTER | 주식회사 케이엠더블유 | 2022-10-27 | — | — | WO | claimed |
| US-11445571-B1 | Tower mounted amplifier (TMA) control based on user equipment (UE) concentration | T-MOBILE INNOVATIONS LLC | 2022-09-13 | — | — | US | claimed |
| US-11431091-B2 | Wireless telecommunication antenna mount and control system and methods of operating the same | RADIARC TECHNOLOGIES, LLC (US) | 2022-08-30 | — | — | US | claimed |
| CN-114553883-A | Cloud edge terminal cooperative data acquisition and privacy protection method and system based on block chain | 北京中科锐链科技有限公司 | 2022-05-27 | — | — | CN | claimed |
| US-11275056-B2 | Method and apparatus for providing real time air measurement applications in wet concrete using dual frequency techniques | CIDRA CORPORATE SERVICES INC. (US) | 2022-03-15 | — | — | US | claimed |
| US-20220034844-A9 | METHOD AND APPARATUS FOR PROVIDING REAL TIME AIR MEASUREMENT APPLICATIONS IN WET CONCRETE USING DUAL FREQUENCY TECHNIQUES | BIESAK JOHN (US) | 2022-02-03 | — | — | US | claimed |