Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114805 | 1.00 | BAZ2B (0.58) | BAZ2BSMN1; SMN2LMNAPABPC1ATM | |
| SCHEMBL21588267 | 0.91 | TRPV1 (0.51) | BAZ2BESR2BRD3 | |
| SCHEMBL5104575 | 0.91 | BAZ2B (0.71) | BAZ2BSMN1; SMN2LMNAPABPC1ATM | |
| SCHEMBL21153987 | 0.90 | BAZ2B (0.47) | BAZ2BSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL16441048 | 0.88 | LMNA (0.62) | BAZ2BSMN1; SMN2LMNAPABPC1ATM | |
| SCHEMBL29983936 | 0.87 | BAZ2B (0.58) | BAZ2BSMN1; SMN2LMNAPABPC1ATM | |
| SCHEMBL3475272 | 0.87 | BAZ2B (0.58) | BAZ2BSMN1; SMN2LMNAPABPC1ATM | |
| SCHEMBL21114768 | 0.86 | BAZ2B (0.61) | BAZ2BSMN1; SMN2LMNAPABPC1ATM | |
| SCHEMBL30506408 | 0.86 | BAZ2B (0.61) | BAZ2BSMN1; SMN2LMNAPABPC1ATM | |
| SCHEMBL31117582 | 0.85 | BAZ2B (0.60) | BAZ2BSMN1; SMN2LMNAPABPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941477-A1 | NOVEL COMPOUNDS FOR THE TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH TAU AGGREGATES | AC Immune SA (CH) | 2022-01-26 | — | — | EP | disclosed |