SCHEMBL29357482

SCHEMBL29357482

N#C/C(=C\c1ccc(O)c(O)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 11/20 1.00
KDM4E B2RXH2 9/20 0.73
ALDH1A1 P00352 8/20 0.73
HPGD P15428 7/20 0.73
MEN1 O00255 7/20 0.73
KMT2A Q03164 7/20 0.73
ERBB2 P04626 6/20 0.73
MAPT P10636 6/20 0.73
TDP1 Q9NUW8 6/20 0.73
TP53 P04637 5/20 0.73
HSD17B10 Q99714 5/20 0.73
CYP1A2 P05177 4/20 0.73
LCK P06239 1/20 0.73
CYP3A4 P08684 5/20 0.69
BLM P54132 5/20 0.69
ALOX15 P16050 4/20 0.69
ALOX12 P18054 4/20 0.69
MAPK1 P28482 4/20 0.69
PMP22 Q01453 4/20 0.69
RECQL P46063 4/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483469 1.00 EGFR (1.00) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL6286665 1.00 EGFR (1.00) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL5908882 1.00 EGFR (1.00) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL17457139 1.00 EGFR (1.00) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL13060220 0.87 EGFR (0.77) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL20995953 0.85 EGFR (0.74) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL20995956 0.85 EGFR (0.74) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL10241964 0.85 EGFR (0.74) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL1705642 0.85 EGFR (1.00) EGFRKDM4EALDH1A1HPGDMEN1
SCHEMBL6285299 0.85 EGFR (1.00) EGFRKDM4EALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118141921-A Use of CAMK2 inhibitors for the preparation of a medicament for reducing resistance to EGFR-driven cancers 四川大学 2024-06-07 CN claimed
CN-117690632-A High-temperature-resistant conductive paste for packaging and preparation method and application thereof 哈尔滨工业大学 2024-03-12 CN claimed
CN-121964383-A Novel medium-temperature sintering pulse energy storage ceramic capacitor dielectric material and preparation method thereof 电子科技大学 2026-05-01 CN disclosed
EP-4663713-A1 BONDED STRUCTURE COMPRISING AN THERMALLY DEBONDABLE ADHESIVE FILM Henkel AG & Co. KGaA (DE) 2025-12-17 EP disclosed
WO-2025242379-A1 BONDED STRUCTURE COMPRISING AN ELECTROCHEMICALLY DEBONDABLE ADHESIVE FILM HENKEL AG & CO. KGAA (DE) 2025-11-27 WO disclosed
US-20250350080-A1 SLIDING CONTACT MATERIAL FOR MOTOR BRUSH, MOTOR BRUSH, AND DIRECT CURRENT MOTOR MABUCHI MOTOR CO., LTD. (JP) 2025-11-13 US disclosed
WO-2025229071-A1 SYNBIOTIC COMBINATION N.V. NUTRICIA (NL) 2025-11-06 WO disclosed
WO-2025229097-A1 SYNBIOTIC MIXTURE FOR YOUNG CHILDREN N.V. NUTRICIA (NL) 2025-11-06 WO disclosed
WO-2025229094-A1 MIXTURE OF NON-DIGESTIBLE SACCHARIDES STIMULATES GUT BARIER N.V. NUTRICIA (NL) 2025-11-06 WO disclosed
WO-2025229072-A1 SYNBIOTIC COMBINATION N.V. NUTRICIA (NL) 2025-11-06 WO disclosed
WO-2025229102-A1 SYNBIOTIC COMBINATION FOR YOUNG CHILDREN N.V. NUTRICIA (NL) 2025-11-06 WO disclosed
US-11324903-B2 To the manufacture and remanufacture of volatile anaesthetic agents using supercritical fluids SAGETECH MEDICAL EQUIPMENT LIMITED (GB) 2022-05-10 US disclosed
CN-114405524-A P-n heterojunction type Pt/TiO2Preparation method of/AgBr/Ag composite photocatalyst 中国科学院东北地理与农业生态研究所 2022-04-29 CN disclosed
EP-3988119-A1 ORALLY-ADMINISTERED PHARMACEUTICAL COMPOSITION FOR ERADICATING ANTIBIOTIC-RESISTANT HELICOBACTER PYLORI, COMPRISING COMPLEX OF NON-ABSORBABLE ANTIBIOTIC AND CLAY MINERAL KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCES (KR) 2022-04-27 EP disclosed
WO-2022079245-A1 3-SUBSTITUTED XANTHINE DERIVATIVES AS MRGPRX4 RECEPTOR MODULATORS RHEINISCHE-FRIEDRICH-WILHELMS-UNIVERSITÄT BONN (DE) 2022-04-21 WO disclosed
CN-114371595-A Wafer-level mask and electroplating process 厦门市三安集成电路有限公司 2022-04-19 CN disclosed
US-11279763-B2 Integrin alpha 9 blockade suppresses lymphatic valve formation and promotes transplant survival THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-22 US disclosed
US-20220064525-A1 DOPED SEMICONDUCTOR NANOCRYSTALS, METHOD FOR PREPARING SAME AND USES THEREOF Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2022-03-03 US disclosed
WO-2022017815-A1 ROOM TEMPERATURE STABLE, ELECTRICALLY CONDUCTIVE 1K EPOXY FORMULATION HENKEL AG & CO. KGAA (DE) 2022-01-27 WO disclosed
EP-3943564-A1 ROOM TEMPERATURE STABLE, ELECTRICALLY CONDUCTIVE 1K EPOXY FORMULATION Henkel AG & Co. KGaA (DE) 2022-01-26 EP disclosed