Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394660 | 1.00 | RAB9A (0.47) | RAB9AFSCN1PGRSMN1; SMN2CSF1R | |
| SCHEMBL22479674 | 0.92 | RAB9A (0.44) | RAB9AFSCN1SMN1; SMN2NPC1F10 | |
| SCHEMBL29354561 | 0.91 | RAB9A (0.44) | RAB9ASMN1; SMN2CSF1RNPC1F10 | |
| SCHEMBL21394549 | 0.91 | RAB9A (0.44) | RAB9ASMN1; SMN2CSF1RNPC1F10 | |
| SCHEMBL21394472 | 0.91 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1F10PARP1 | |
| SCHEMBL29358624 | 0.91 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1F10PARP1 | |
| SCHEMBL21394586 | 0.90 | RAB9A (0.47) | RAB9ASMN1; SMN2CSF1RNPC1F10 | |
| SCHEMBL29357018 | 0.90 | RAB9A (0.42) | RAB9ASMN1; SMN2F10PARP1 | |
| SCHEMBL21394588 | 0.90 | RAB9A (0.42) | RAB9ASMN1; SMN2F10PARP1 | |
| SCHEMBL21394773 | 0.89 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1F10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |