SCHEMBL29358680

SCHEMBL29358680

Cc1ccccc1C#Cc1ccc(CCC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 1.00
FFAR4 Q5NUL3 3/20 1.00
CHRM2 P08172 1/20 1.00
S1PR1 P21453 1/20 1.00
FPR1 P21462 1/20 1.00
FPR3 P25089 1/20 1.00
GPR183 P32249 1/20 1.00
APLNR P35414 1/20 1.00
GPR65 Q8IYL9 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1551461 1.00 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL19821417 0.92 FFAR1 (0.84) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550951 0.89 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL14924233 0.88 FFAR1 (0.79) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1551052 0.85 FFAR1 (0.73) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1551253 0.84 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550207 0.84 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1551391 0.84 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550727 0.84 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550924 0.83 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171512-A1 FGF21 VARIANTS SANOFI SA (FR) 2025-05-29 US disclosed
US-20250121034-A1 STABILIZED PHARMACEUTICAL FORMULATIONS OF INSULIN ANALOGUES AND/OR INSULIN DERIVATIVES SANOFI SA (FR) 2025-04-17 US disclosed
US-20240366727-A1 FGF21 COMPOUND / GLP-1R AGONIST COMBINATIONS WITH OPTIMIZED ACTIVITY RATIO SANOFI SA (FR) 2024-11-07 US disclosed
US-20240360194-A1 New Peptides as Potent and Selective GIP Receptor Agonists SANOFI (FR) 2024-10-31 US disclosed
US-20240325499-A1 FGF21 COMPOUND / GLP-1R AGONIST COMBINATIONS WITH OPTIMIZED ACTIVITY RATIO SANOFI SA (FR) 2024-10-03 US disclosed
US-20240316085-A1 METHODS, AGENTS, AND DEVICES FOR LOCAL NEUROMODULATION OF AUTONOMIC NERVES Tulavi Therapeutics, Inc. 2024-09-26 US disclosed
EP-4399224-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS Sanofi (FR) 2024-07-17 EP disclosed
US-12029733-B2 Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system Tulavi Therapeutics, Inc. (US) 2024-07-09 US disclosed
CN-118159552-A Novel peptides as potent and selective GIP receptor agonists 赛诺菲 2024-06-07 CN disclosed
CN-109996557-B Novel compounds as peptide GLP 1/glucagon/GIP receptor agonists 赛诺菲 2024-05-03 CN disclosed
US-20220280497-A1 TREATMENT OF SEPSIS AND RELATED INFLAMMATORY CONDITIONS BY LOCAL NEUROMODULATION OF THE AUTONOMIC NERVOUS SYSTEM Tulavi Therapeutics, Inc. 2022-09-08 US disclosed
CN-114939156-A Stabilized pharmaceutical formulations of insulin aspart 赛诺菲 2022-08-26 CN disclosed
US-20220227825-A1 FGF21 VARIANTS SANOFI SA (FR) 2022-07-21 US disclosed
CN-105899190-B Stabilized pharmaceutical formulations of insulin aspart 赛诺菲 2022-06-14 CN disclosed
US-20220175710-A1 COMBINATION THERAPY AKERSHUS UNIVERSITETSSYKEHUS HF (NO) 2022-06-09 US disclosed
CN-108026153-B Novel exendin-4 derivatives as selective peptide dual GLP-1/glucagon receptor agonists 赛诺菲 2022-05-27 CN disclosed
EP-3955906-A1 COMBINATION THERAPY COMPRISING AN FFAR4 AGONIST AND AN ALPHA-7 NACHR AGONIST OR POSITIVE MODULATOR Akershus Universitetssykehus HF (NO) 2022-02-23 EP disclosed
US-11246879-B2 Methods, agents, and devices for local neuromodulation of autonomic nerves Tulai Therapeutics, Inc. (US) 2022-02-15 US disclosed
US-20220040267-A1 STABILIZED PHARMACEUTICAL FORMULATIONS OF INSULIN ANALOGUES AND/OR INSULIN DERIVATIVES SANOFI SA (FR) 2022-02-10 US disclosed
US-20220023392-A1 STABILIZED PHARMACEUTICAL FORMULATIONS OF INSULIN ASPART SANOFI SA (FR) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360194-A1 New Peptides as Potent and Selective GIP Receptor Agonists GIPR, GLP1R, GPR119 FFAR1 134/4885FFAR4 111/4885CHRM2 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.