Zinc Chloride

Zinc Chloride

SCHEMBL29359017

Cc1cc(Cl)ccc1[N+]#N.Cc1cc(Cl)ccc1[N+]#N.Cl[Zn]Cl.[Cl-].[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Zinc Chloride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
NOX1 Q9Y5S8 1/20 0.33
CYP2A6 P11509 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
NOTUM Q6P988 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
RAPGEF4 Q8WZA2 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL239363 0.94 CYP3A4 (0.40) CYP3A4NOX1CYP2A6GAANOTUM
Hydrochloric Acid SCHEMBL10636134 0.92 CYP3A4 (0.39) CYP3A4NOX1CYP2A6GAANOTUM
Hydrochloric Acid SCHEMBL10636139 0.92 CYP3A4 (0.39) CYP3A4NOX1CYP2A6GAANOTUM
SCHEMBL111298 0.92 CYP3A4 (0.41) CYP3A4NOX1CYP2A6GAANOTUM
SCHEMBL9947629 0.85 CYP3A4 (0.36) CYP3A4NOX1CYP2A6GAANOTUM
SCHEMBL1086598 0.85 CYP3A4 (0.36) CYP3A4NOX1CYP2A6GAANOTUM
Acetic Acid SCHEMBL38654826 0.80 FLT1 (0.38) NOX1NOTUMTSHRHTR2AHTR2C
Hydrochloric Acid SCHEMBL8498880 0.78 CYP3A4 (0.45) CYP3A4CYP2A6ALDH1A1GAAPOLB
SCHEMBL8497290 0.75 CYP3A4 (0.46) CYP3A4CYP2A6ALDH1A1GAAPOLB
SCHEMBL31351880 0.75 CYP3A4 (0.46) CYP3A4CYP2A6ALDH1A1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3295173-B1 COMPOSITIONS AND METHODS FOR SIMULTANEOUS INACTIVATION OF ALKALINE PHOSPHATASE AND PEROXIDASE ENZYMES DURING AUTOMATED MULTIPLEX TISSUE STAINING ASSAYS VENTANA MED SYST INC (US) 2025-11-05 EP disclosed
US-20240328910-A1 COMPOSITIONS AND METHODS FOR SIMULTANEOUS INACTIVATION OF ALKALINE PHOSPHATASE AND PEROXIDASE ENZYMES DURING AUTOMATED MULTIPLEX TISSUE STAINING ASSAYS VENTANA MED SYST INC (US) 2024-10-03 US disclosed
CN-114457141-B Quantitative detection kit for prostatic acid phosphatase 北京九强生物技术股份有限公司 2024-05-24 CN disclosed
US-11971337-B2 Compositions and methods for simultaneous inactivation of alkaline phosphatase and peroxidase enzymes during automated multiplex tissue staining assays VENTANA MEDICAL SYSTEMS, INC. (US) 2024-04-30 US disclosed
CN-114457141-A Quantitative detection kit for prostatic acid phosphatase 北京九强生物技术股份有限公司 2022-05-10 CN disclosed
US-20220026319-A1 COMPOSITIONS AND METHODS FOR SIMULTANEOUS INACTIVATION OF ALKALINE PHOSPHATASE AND PEROXIDASE ENZYMES DURING AUTOMATED MULTIPLEX TISSUE STAINING ASSAYS VENTANA MEDICAL SYSTEMS, INC. (US) 2022-01-27 US disclosed