SCHEMBL29359135

SCHEMBL29359135

C[C@@H](O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 6/20 0.62
▸ GHSR Q92847 3/20 0.62
▸ IL23R Q5VWK5 5/20 0.59
▸ IL1RN P18510 1/20 0.58
▸ ERAP2 Q6P179 1/20 0.58
▸ NPY1R P25929 1/20 0.57
▸ NPY2R P49146 1/20 0.57
▸ NPY4R P50391 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31619557 0.97 IL23R (0.64) KISS1RGHSRIL23R
SCHEMBL30276251 0.97 IL23R (0.64) KISS1RGHSRIL23R
SCHEMBL30276253 0.96 GHSR (0.64) KISS1RGHSRIL23R
SCHEMBL29551293 0.96 GHSR (0.64) KISS1RGHSRIL23R
SCHEMBL30276276 0.96 GHSR (0.63) KISS1RGHSRIL23R
SCHEMBL30379397 0.95 IL23R (0.64) KISS1RGHSRIL23R
SCHEMBL38662290 0.95 IL23R (0.64) KISS1RGHSRIL23R
SCHEMBL30276250 0.95 IL23R (0.65) KISS1RGHSRIL23RNPY1RNPY2R
SCHEMBL30276213 0.95 IL23R (0.65) KISS1RGHSRIL23RNPY1RNPY2R
SCHEMBL30276242 0.94 IL23R (0.63) KISS1RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025188678-A9 ICAM-1 TARGETED CAR CONSTRUCTS AND METHODS OF TREATMENT AffyImmune Therapeutics Inc. (US) 2025-11-27 — — WO claimed
US-20250288611-A1 ICAM-1 TARGETED CAR CONSTRUCTS AND METHODS OF TREATMENT AffyImmune Therapeutics Inc. 2025-09-18 — — US claimed
US-20250288611-A1 ICAM-1 TARGETED CAR CONSTRUCTS AND METHODS OF TREATMENT AffyImmune Therapeutics Inc. 2025-09-18 — — US disclosed
US-11458206-B2 Targeted conjugates and particles and formulations thereof TVA (ABC), LLC (US) 2022-10-04 — — US disclosed
US-20220251143-A1 NON-HYDROLYZABLE NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF UNIV COLUMBIA (US) 2022-08-11 — — US disclosed
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-03-31 — — US disclosed
US-20220054647-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-02-24 — — US disclosed
CN-108473538-B SSTR targeting conjugates and particles and formulations thereof 塔弗达治疗有限公司 2022-01-28 — — CN disclosed
EP-3941508-A1 NON-HYDROLYZABLE, NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF The Trustees of Columbia University in the City of New York (US) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054647-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR3 KISS1R 64/4885GHSR 13/4885IL23R 778/4885
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR3 KISS1R 64/4885GHSR 13/4885IL23R 778/4885
US-11458206-B2 Targeted conjugates and particles and formulations thereof SSTR5, SSTR1, SSTR4 KISS1R 70/4885GHSR 19/4885IL23R 420/4885
US-20220251143-A1 NON-HYDROLYZABLE NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF SSTR4, SSTR1, SSTR5 KISS1R 478/4885GHSR 13/4885IL23R 378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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