Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 7/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291553 | 0.83 | GAA (0.43) | PIK3CAPIK3CBACACBATR | |
| SCHEMBL30291447 | 0.83 | GAA (0.43) | PIK3CAPIK3CBACACBATR | |
| SCHEMBL22468369 | 0.82 | ATR (0.39) | NR3C2LRRK2PIK3CAPIK3CBACACB | |
| SCHEMBL22488432 | 0.82 | ATR (0.39) | NR3C2LRRK2PIK3CAPIK3CBACACB | |
| SCHEMBL22468367 | 0.82 | ATR (0.39) | NR3C2LRRK2PIK3CAPIK3CBACACB | |
| SCHEMBL28693923 | 0.82 | ATR (0.39) | NR3C2LRRK2PIK3CAPIK3CBACACB | |
| SCHEMBL28693920 | 0.82 | ATR (0.39) | NR3C2LRRK2PIK3CAPIK3CBACACB | |
| SCHEMBL2131669 | 0.73 | HTR3E (0.51) | KIF18ANR3C2PIK3CAPIK3CB | |
| SCHEMBL22121194 | 0.72 | NR3C2 (0.48) | KIF18ANR3C2LRRK2PIK3CAPIK3CB | |
| SCHEMBL31696843 | 0.72 | NR3C2 (0.48) | KIF18ANR3C2LRRK2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941922-A1 | INHIBITORS OF RAF KINASES | Kinnate Biopharma Inc. (US) | 2022-01-26 | — | — | EP | disclosed |