Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522375 | 0.92 | ELANE (0.70) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| Parietin SCHEMBL29356669 | 0.86 | MAPT (0.66) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| Parietin SCHEMBL16226462 | 0.86 | MAPT (0.66) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL16226194 | 0.86 | ELANE (0.69) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL23522398 | 0.84 | ELANE (0.54) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL16226377 | 0.84 | ELANE (0.70) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| Alterporriol Q SCHEMBL23522419 | 0.83 | ELANE (0.56) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| Alterporriol Q SCHEMBL29356749 | 0.83 | ELANE (0.56) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL16227260 | 0.80 | ELANE (0.61) | ELANEALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL16226813 | 0.80 | ELANE (0.61) | ELANEALDH1A1MAPTKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | disclosed |