Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | ACLY | P53396 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alterporriol Q SCHEMBL23522419 | 1.00 | ELANE (0.56) | ELANEALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL23522398 | 0.92 | ELANE (0.54) | ELANEALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL23522375 | 0.86 | ELANE (0.70) | ELANEALDH1A1MAPTALOX15KDM4E | |
| Macrosporin SCHEMBL30237810 | 0.84 | ELANE (0.68) | ELANEALDH1A1MAPTALOX15KDM4E | |
| Macrosporin SCHEMBL16227189 | 0.84 | ELANE (0.68) | ELANEALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL23198984 | 0.84 | ELANE (0.68) | ELANEALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL29360014 | 0.83 | ELANE (0.60) | ELANEALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL16226377 | 0.80 | ELANE (0.70) | ELANEALDH1A1MAPTALOX15KDM4E | |
| Alterporriol C SCHEMBL29359613 | 0.79 | NFKB1 (0.70) | ELANEALDH1A1MAPTALOX15KDM4E | |
| Parietin SCHEMBL16226462 | 0.78 | MAPT (0.66) | ELANEALDH1A1MAPTALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | disclosed |