SCHEMBL29360255

SCHEMBL29360255

Cc1cccc(-c2ccccc2O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.58
CNR1 P21554 3/20 0.58
ALDH1A1 P00352 1/20 0.58
HPGD P15428 1/20 0.58
BCL2L1 Q07817 1/20 0.58
HSD17B10 Q99714 1/20 0.58
ESR2 Q92731 1/20 0.48
PTPN5 P54829 1/20 0.47
ACHE P22303 2/20 0.46
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
PDK2 Q15119 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
APP P05067 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2411804 1.00 CNR2 (0.58) CNR2CNR1ALDH1A1HPGDBCL2L1
SCHEMBL20721787 0.92 CNR2 (0.51) CNR2CNR1ALDH1A1HPGDBCL2L1
SCHEMBL17759045 0.89 CNR2 (0.49) CNR2CNR1ALDH1A1HPGDBCL2L1
Pyrimidine SCHEMBL29073747 0.88 CNR2 (0.49) CNR2CNR1ALDH1A1HPGDBCL2L1
SCHEMBL28773599 0.87 CNR2 (0.51) CNR2CNR1ALDH1A1HPGDBCL2L1
SCHEMBL30522729 0.86 CA12 (0.51) CNR2CNR1ALDH1A1HPGDBCL2L1
SCHEMBL30522728 0.86 CA12 (0.51) CNR2CNR1ALDH1A1HPGDBCL2L1
SCHEMBL9742510 0.86 ALOX15 (0.50) CNR2CNR1ALDH1A1HPGDHSD17B10
SCHEMBL1007613 0.86 CA12 (0.51) CNR2CNR1ALDH1A1HPGDBCL2L1
SCHEMBL29035128 0.85 CNR2 (0.60) CNR2CNR1ACHECA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4228632-A2 REV-ERB AGONISTS Saint Louis University (US) 2023-08-23 EP disclosed
CN-116635029-A REV-ERB agonists 圣路易斯大学 2023-08-22 CN disclosed
CN-116194552-A Cyclic phosphazene compounds having oxaphosphaphenanthrene-containing ring structure 株式会社伏见制药所 2023-05-30 CN disclosed
CN-113337425-B Gordoniella for producing long-carbon-chain mycolic acid and application thereof 山东科技大学 2022-08-02 CN disclosed
WO-2022093552-A9 REV-ERB AGONISTS Saint Louis Univeristy (US) 2022-06-23 WO disclosed
WO-2022093552-A2 REV-ERB AGONISTS Saint Louis Univeristy (US) 2022-05-05 WO disclosed
WO-2022019021-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE 株式会社伏見製薬所 2022-01-27 WO disclosed