Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24832763 | 0.85 | GPR35 (0.71) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL17943796 | 0.85 | GPR35 (0.71) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL12735466 | 0.85 | GPR35 (0.71) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL24832764 | 0.85 | GPR35 (0.71) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL12652469 | 0.85 | GPR35 (0.71) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL12652654 | 0.84 | GPR35 (0.67) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL20870811 | 0.84 | GPR35 (0.67) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL20870531 | 0.82 | GPR35 (0.67) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL12941097 | 0.82 | GPR35 (0.67) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL19393292 | 0.82 | GPR35 (0.70) | GPR35NPC1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11402380-B2 | Assays for detecting antibodies capable of mediating antibody-dependent cell-mediated cytotoxicity | EMORY UNIVERSITY (US) | 2022-08-02 | — | — | US | disclosed |
| WO-2022016690-A1 | LUCIFERASE SUBSTRATES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2022-01-27 | — | — | WO | disclosed |