SCHEMBL29361007

SCHEMBL29361007

Cc1cccc(C(C)(C)c2cccc(C)c2O)c1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.75
GABRB2 P47870 2/20 0.75
ALDH1A1 P00352 4/20 0.59
CA2 P00918 3/20 0.52
TRPA1 O75762 2/20 0.52
ATM Q13315 2/20 0.46
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP2C9 P11712 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 1/20 0.40
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
KMT2A Q03164 2/20 0.37
ALOX12 P18054 1/20 0.37
CYP3A4 P08684 1/20 0.37
ESR1 P03372 2/20 0.37
CYP2A6 P11509 1/20 0.36
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120430 1.00 GABRA1 (0.75) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL29407049 0.86 GABRA1 (1.00) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL56224 0.86 GABRA1 (1.00) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL10550628 0.86 GABRA1 (0.62) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL11130480 0.86 GABRA1 (0.62) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL17712324 0.84 GABRA1 (0.60) GABRA1GABRB2ALDH1A1CA2TRPA1
Hydrogen Sulfide SCHEMBL1353453 0.84 GABRA1 (0.95) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL28119496 0.84 GABRA1 (0.95) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL28297717 0.84 GABRA1 (0.95) GABRA1GABRB2ALDH1A1CA2TRPA1
SCHEMBL28015936 0.84 GABRA1 (0.95) GABRA1GABRB2ALDH1A1CA2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12040604-B2 Composite reinforcement systems for power transmissionlines, and methods of forming same Gridwrap, Inc. (US) 2024-07-16 US disclosed
US-20220029405-A1 COMPOSITE REINFORCEMENT SYSTEMS FOR POWER TRANSMISSIONLINES, AND METHODS OF FORMING SAME ZAMANI DAVOUD (US) 2022-01-27 US disclosed