Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 10/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028651 | 1.00 | GSK3B (0.50) | GSK3BDYRK1ANFATC1ARCDK2 | |
| SCHEMBL25029340 | 0.86 | GSK3B (0.47) | GSK3BDYRK1ANFATC1ARCDK2 | |
| SCHEMBL29365109 | 0.86 | GSK3B (0.47) | GSK3BDYRK1ANFATC1ARCDK2 | |
| SCHEMBL25028830 | 0.86 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1ARCDK2 | |
| SCHEMBL29363648 | 0.85 | GSK3B (0.52) | GSK3BDYRK1ANFATC1ARCDK2 | |
| SCHEMBL25027634 | 0.85 | GSK3B (0.52) | GSK3BDYRK1ANFATC1ARCDK2 | |
| SCHEMBL29364138 | 0.83 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL25029164 | 0.83 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1ARSLC6A4 | |
| SCHEMBL25029171 | 0.82 | DYRK1A (0.58) | GSK3BDYRK1ANFATC1ARCDK2 | |
| SCHEMBL29364491 | 0.82 | DYRK1A (0.58) | GSK3BDYRK1ANFATC1ARCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |