Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 5/20 | 0.42 |
| ▸ | CCNK | O75909 | 5/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.42 |
| ▸ | CDK2 | P24941 | 5/20 | 0.42 |
| ▸ | CDK9 | P50750 | 5/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CCNH | P51946 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25027642 | 0.92 | GSK3B (0.47) | CCNT1CCNKCCNE1CDK2CDK9 | |
| Trifluoroacetic Acid SCHEMBL29361361 | 0.91 | CCNT1 (0.48) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29362063 | 0.86 | GSK3B (0.45) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25029249 | 0.86 | GSK3B (0.45) | CCNT1CCNKCCNE1CDK2CDK9 | |
| Trifluoroacetic Acid SCHEMBL29363835 | 0.85 | CCNT1 (0.46) | CCNT1CCNKCCNE1CDK2CDK9 | |
| Trifluoroacetic Acid SCHEMBL29361434 | 0.84 | GSK3B (0.38) | CCNT1CCNKCCNE1CDK2CDK9 | |
| Trifluoroacetic Acid SCHEMBL29005438 | 0.83 | CCNT1 (0.42) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25028661 | 0.83 | GSK3B (0.48) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29364439 | 0.83 | GSK3B (0.48) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL25213035 | 0.82 | GPR119 (0.44) | GSK3BDYRK1ANFATC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |