Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18838514 | 1.00 | DRD4 (0.51) | DRD4KCNH2UTS2RSIGMAR1OPRM1 | |
| SCHEMBL29363908 | 0.91 | DRD4 (0.53) | DRD4KCNH2UTS2RSIGMAR1MEN1 | |
| SCHEMBL18838422 | 0.91 | DRD4 (0.53) | DRD4KCNH2UTS2RSIGMAR1MEN1 | |
| SCHEMBL18838401 | 0.91 | KMT2A (0.54) | DRD4KCNH2UTS2RSIGMAR1MEN1 | |
| SCHEMBL18860277 | 0.89 | DRD4 (0.51) | DRD4KCNH2UTS2RSIGMAR1MEN1 | |
| SCHEMBL18838376 | 0.88 | KCNH2 (0.60) | DRD4KCNH2SIGMAR1OPRM1OPRD1 | |
| SCHEMBL18838506 | 0.87 | HTR2A (0.54) | DRD4KCNH2SIGMAR1OPRM1OPRD1 | |
| SCHEMBL29364658 | 0.82 | KCNH2 (0.60) | KCNH2UTS2ROPRM1OPRD1OPRK1 | |
| SCHEMBL18838420 | 0.82 | KCNH2 (0.60) | KCNH2UTS2ROPRM1OPRD1OPRK1 | |
| SCHEMBL18838407 | 0.82 | KCNH2 (0.53) | DRD4KCNH2SIGMAR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289886-B | Ion channel inhibiting compounds, pharmaceutical formulations and uses | 安华赛公司 | 2022-01-28 | — | — | CN | disclosed |