Vorozole

Vorozole

SCHEMBL29363602

Cn1nnc2ccc([C@H](c3ccc(Cl)cc3)n3cncn3)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 20/20 1.00
CYP11B1 P15538 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rac-Vorozole SCHEMBL13223107 1.00 CYP19A1 (1.00) CYP19A1CYP11B1
[N-Methyl-11C]Vorozole SCHEMBL12171619 1.00 CYP19A1 (1.00) CYP19A1CYP11B1
Rac-Vorozole SCHEMBL29606650 1.00 CYP19A1 (1.00) CYP19A1CYP11B1
Vorozole SCHEMBL4554 1.00 CYP19A1 (1.00) CYP19A1CYP11B1
Rac-Vorozole SCHEMBL1552681 1.00 CYP19A1 (1.00) CYP19A1CYP11B1
Vorozole SCHEMBL19127035 0.92 CYP19A1 (0.84) CYP19A1CYP11B1
SCHEMBL13223109 0.91 CYP19A1 (0.83) CYP19A1CYP11B1
SCHEMBL13223108 0.91 CYP19A1 (0.83) CYP19A1CYP11B1
SCHEMBL3871739 0.86 CYP19A1 (0.76) CYP19A1CYP11B1
Oxalic Acid SCHEMBL9524494 0.84 CYP19A1 (0.72) CYP19A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645742-B1 ANTI-ROR1 ANTIBODIES AND METHODS OF MAKING AND USING THEREOF SYSTIMMUNE INC (US) 2026-04-29 EP claimed
US-20250145573-A1 COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING CANCER CKP THERAPEUTICS, INC. 2025-05-08 US claimed
EP-3139928-B1 ANORDRIN COMPOSITIONS AND METHODS FOR TREATING DISEASES SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RES (CN) 2025-03-05 EP claimed
EP-3928836-B1 N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-09-18 EP claimed
US-20240148713-A1 COMPOSITION FOR TREATMENT OF ANTICANCER DRUG RESISTANCE INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2024-05-09 US claimed
EP-4295848-A1 COMPOSITION FOR TREATMENT OF ANTICANCER DRUG RESISTANCE Industry-Academic Cooperation Foundation, Yonsei University (KR) 2023-12-27 EP claimed
EP-3373967-B9 TREATMENT OF ER-NEGATIVE BREAST CANCER WITH AN PDGF-CC INHIBITOR AND AN ANTI ESTROGEN PARACRINE THERAPEUTICS AB (SE) 2023-10-04 EP claimed
EP-3209301-B1 METHODS OF REDUCING MAMMOGRAPHIC BREAST DENSITY AND/OR BREAST CANCER RISK HAVAH THERAPEUTICS PTY LTD (AU) 2023-06-07 EP claimed
EP-3373967-B1 TREATMENT OF ER-NEGATIVE BREAST CANCER WITH AN PDGF-CC INHIBITOR AND AN ANTI ESTROGEN PARACRINE THERAPEUTICS AB (SE) 2023-06-07 EP claimed
EP-3441089-B1 TREATMENT METHODS USING ADENOVIRUS VASCULAR BIOGENICS LTD (IL) 2022-12-14 EP claimed
WO-2022177290-A1 COMPOSITION FOR TREATMENT OF ANTICANCER DRUG RESISTANCE 연세대학교 산학협력단 2022-08-25 WO claimed
EP-3426657-B1 2 AMINO N [7 METHOXY 2, 3-DIHYDROIMIDAZO-[1, 2-C]QUINAZOLIN-5-YL]PYRIMIDINE 5 CARBOXAMIDES Bayer Pharma AG (DE) 2022-07-13 EP claimed
WO-2026106969-A1 NOVEL INHIBITORS OF INTERLEUKIN RECEPTOR- ASSOCIATED KINASE UNIVERSITY OF ROCHESTER (US) 2026-05-21 WO disclosed
EP-4706684-A2 COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF IMMUNOTHERAPIES AND VACCINES The Regents of The University of Michigan (US) 2026-03-11 EP disclosed
EP-4034253-B1 COMPOSITIONS FOR INCREASING THE EFFICACY OF IMMUNOTHERAPIES AND VACCINES UNIV MICHIGAN REGENTS (US) 2026-01-21 EP disclosed
EP-4604947-A2 COMPOSITIONS AND METHODS FOR PREVENTING CARDIOMYOPATHY Ohio State Innovation Foundation (US) 2025-08-27 EP disclosed
US-11311538-B2 Compositions and methods for targeting cancers YALE UNIVERSITY (US) 2022-04-26 US disclosed
WO-2022055285-A1 PHARMACEUTICAL COMPOSITION FOR KILLING CANCER PROGENITOR CELLS 연세대학교 산학협력단 2022-03-17 WO disclosed
CN-114173814-A Composition for preventing, ameliorating or treating immune checkpoint inhibitor-resistant cancer 古德T细胞有限公司 2022-03-11 CN disclosed
WO-2022020661-A1 INHIBITORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES 1 AND 4 THE UNIVERSITY OF ROCHESTER (US) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148713-A1 COMPOSITION FOR TREATMENT OF ANTICANCER DRUG RESISTANCE ABCC1, MCL1, SLC11A2 CYP19A1 985/4885CYP11B1 1836/4885
US-20250145573-A1 COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING CANCER ABCC1, BRCA1, TP53 CYP19A1 1209/4885CYP11B1 1131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.