Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.61 |
| ▸ | CACNA1I | Q9P0X4 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18838392 | 1.00 | KCNH2 (0.61) | KCNH2CACNA1IMEN1KMT2AMCHR1 | |
| SCHEMBL18838325 | 0.89 | KCNH2 (0.62) | KCNH2CACNA1ICACNA1HCACNA1GCHRM2 | |
| SCHEMBL18838348 | 0.87 | KCNH2 (0.48) | KCNH2CACNA1IMEN1KMT2AHTR1A | |
| SCHEMBL18838368 | 0.87 | CARM1 (0.46) | KCNH2CACNA1IMEN1KMT2AMCHR1 | |
| SCHEMBL18838388 | 0.87 | KCNH2 (0.46) | KCNH2CACNA1IHTR1AHTR7 | |
| SCHEMBL18838420 | 0.87 | KCNH2 (0.60) | KCNH2CACNA1IMEN1KMT2ACACNA1H | |
| SCHEMBL29364658 | 0.87 | KCNH2 (0.60) | KCNH2CACNA1IMEN1KMT2ACACNA1H | |
| SCHEMBL18838353 | 0.86 | KCNH2 (0.48) | KCNH2CACNA1IMEN1KMT2APOLB | |
| SCHEMBL18838355 | 0.85 | KCNH2 (0.44) | KCNH2CACNA1IL3MBTL1GRM5 | |
| SCHEMBL29361679 | 0.85 | KCNH2 (0.44) | KCNH2CACNA1IL3MBTL1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289886-B | Ion channel inhibiting compounds, pharmaceutical formulations and uses | 安华赛公司 | 2022-01-28 | — | — | CN | disclosed |