Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029067 | 1.00 | GSK3B (0.46) | GSK3BDYRK1ANFATC1MEN1KMT2A | |
| SCHEMBL26180175 | 0.83 | MAPK1 (0.32) | LRRK2SOS1 | |
| SCHEMBL29005446 | 0.80 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CDK2CCNT1 | |
| SCHEMBL26180188 | 0.80 | DYRK1A (0.49) | GSK3BDYRK1ANFATC1CDK2CCNT1 | |
| SCHEMBL29364483 | 0.80 | MEN1 (0.49) | GSK3BDYRK1ANFATC1MEN1KMT2A | |
| SCHEMBL25029238 | 0.80 | MEN1 (0.49) | GSK3BDYRK1ANFATC1MEN1KMT2A | |
| SCHEMBL26719362 | 0.79 | GSK3B (0.49) | GSK3BDYRK1ANFATC1MEN1KMT2A | |
| SCHEMBL29365109 | 0.78 | GSK3B (0.47) | GSK3BDYRK1ANFATC1CDK2CCNT1 | |
| SCHEMBL25029340 | 0.78 | GSK3B (0.47) | GSK3BDYRK1ANFATC1CDK2CCNT1 | |
| SCHEMBL25028691 | 0.77 | DYRK1A (0.44) | GSK3BDYRK1ANFATC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |