Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26180101 | 1.00 | PDE4B (0.51) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18318290 | 0.93 | PDE4B (0.53) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL22953433 | 0.88 | PDE4B (0.52) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29363719 | 0.87 | GPR119 (0.58) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20439351 | 0.87 | GPR119 (0.58) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20439353 | 0.87 | GPR119 (0.58) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL279184 | 0.85 | PDE4B (0.49) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3400187 | 0.85 | PDE4B (0.49) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL38662418 | 0.85 | PDE4B (0.49) | PDE4BUSP30 | |
| SCHEMBL3400190 | 0.85 | PDE4B (0.49) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |