Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | NRAS | P01111 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 6/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 6/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 6/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029229 | 1.00 | SLC6A4 (0.49) | SLC6A4GSK3BDYRK1ASLC6A2KCNH2 | |
| SCHEMBL25028896 | 0.86 | GSK3B (0.45) | SLC6A4GSK3BDYRK1ASLC6A2KCNH2 | |
| SCHEMBL25029015 | 0.85 | GSK3B (0.47) | SLC6A4GSK3BDYRK1ANFATC1CCNT1 | |
| SCHEMBL29362012 | 0.85 | GSK3B (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL26180176 | 0.85 | GSK3B (0.47) | GSK3BDYRK1ASLC6A2NFATC1CCNT1 | |
| SCHEMBL25029240 | 0.85 | GSK3B (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL29363716 | 0.83 | SLC6A4 (0.48) | SLC6A4GSK3BDYRK1ASLC6A2KCNH2 | |
| SCHEMBL25029029 | 0.83 | SLC6A4 (0.48) | SLC6A4GSK3BDYRK1ASLC6A2KCNH2 | |
| SCHEMBL29363798 | 0.83 | CCNT1 (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL25029275 | 0.83 | CCNT1 (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |