Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029240 | 1.00 | GSK3B (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL25029015 | 0.89 | GSK3B (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL26180176 | 0.89 | GSK3B (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL29363798 | 0.86 | CCNT1 (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL25029275 | 0.86 | CCNT1 (0.47) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL25029229 | 0.85 | SLC6A4 (0.49) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL29364398 | 0.85 | SLC6A4 (0.49) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL26717234 | 0.84 | NOS3 (0.48) | GSK3BDYRK1ANFATC1CCNT1CCNK | |
| SCHEMBL29364049 | 0.83 | GSK3B (0.44) | GSK3BDYRK1ACCNT1CCNKCCNE1 | |
| SCHEMBL25029333 | 0.83 | GSK3B (0.44) | GSK3BDYRK1ACCNT1CCNKCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |