Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934582 | 0.85 | TP53 (0.51) | RXRARXRBTP53CYP3A4MAP4K4 | |
| SCHEMBL2934501 | 0.82 | TDP1 (0.47) | TP53CYP3A4LMNAMAPTKMT2A | |
| SCHEMBL2939441 | 0.70 | HDAC4 (0.57) | CYP3A4GAAMAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2938124 | 0.69 | HDAC4 (0.55) | CYP3A4GAAMAPTKMT2AMEN1 | |
| SCHEMBL11017769 | 0.67 | RXRA (0.51) | RXRARXRBTP53CYP3A4MAP4K4 | |
| SCHEMBL398405 | 0.67 | TP53 (0.56) | RXRARXRBTP53CYP3A4MAP4K4 | |
| SCHEMBL9260410 | 0.67 | RXRA (0.66) | RXRARXRBTP53CYP3A4MAP4K4 | |
| SCHEMBL29426410 | 0.67 | RXRA (0.66) | RXRARXRBTP53CYP3A4MAP4K4 | |
| SCHEMBL5688174 | 0.66 | TP53 (0.60) | RXRARXRBTP53CYP3A4MAP4K4 | |
| SCHEMBL1337788 | 0.66 | TP53 (0.65) | RXRARXRBTP53CYP3A4MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |