Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623480 | 0.87 | MAPK1 (0.41) | MAPK1CNR1S1PR3S1PR1KMT2A | |
| SCHEMBL29364920 | 0.83 | S1PR1 (0.39) | MAPK1CNR1S1PR3S1PR1CYP3A4 | |
| SCHEMBL28890918 | 0.82 | CYP3A4 (0.46) | MAPK1CYP3A4KMT2AMEN1TP53 | |
| SCHEMBL16169582 | 0.79 | ALDH1A1 (0.41) | MAPK1CYP3A4KMT2AMEN1MAPT | |
| SCHEMBL17055570 | 0.77 | PSEN1 (0.41) | MAPTAGPAT2IDH1 | |
| SCHEMBL15308430 | 0.76 | GAA (0.38) | S1PR3S1PR1CYP3A4KMT2AMEN1 | |
| SCHEMBL3231488 | 0.76 | AKR1C3 (0.40) | MAPK1S1PR3S1PR1AGPAT2IGF1R | |
| SCHEMBL2882112 | 0.76 | GRIK1 (0.42) | MAPK1CNR1KMT2AMEN1MAPT | |
| SCHEMBL1980176 | 0.76 | CNR1 (0.47) | MAPK1CNR1KMT2AMEN1TP53 | |
| SCHEMBL2514419 | 0.75 | IDO1 (0.40) | S1PR3CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979835-A | Synthetic method of pazopanib trimer impurity intermediate | 重庆医科大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113979835-A | Synthetic method of pazopanib trimer impurity intermediate | 重庆医科大学 | 2022-01-28 | — | — | CN | disclosed |