Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 12/20 | 0.37 |
| ▸ | TGFBR2 | P37173 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | EPHB1 | P54762 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23007900 | 1.00 | TGFBR1 (0.37) | TGFBR1TGFBR2ATMCYP2C9IKBKB | |
| SCHEMBL23007873 | 0.93 | TGFBR1 (0.35) | TGFBR1TGFBR2ROCK1 | |
| SCHEMBL29363244 | 0.91 | TGFBR1 (0.39) | TGFBR1TGFBR2 | |
| SCHEMBL23007895 | 0.91 | TGFBR1 (0.39) | TGFBR1TGFBR2 | |
| SCHEMBL23007865 | 0.90 | TGFBR1 (0.38) | TGFBR1TGFBR2 | |
| SCHEMBL29363779 | 0.90 | TGFBR1 (0.38) | TGFBR1TGFBR2 | |
| SCHEMBL23007899 | 0.90 | TGFBR1 (0.38) | TGFBR1TGFBR2 | |
| SCHEMBL23007688 | 0.90 | TGFBR1 (0.39) | TGFBR1TGFBR2 | |
| SCHEMBL23007864 | 0.90 | TGFBR1 (0.35) | TGFBR1TGFBR2 | |
| SCHEMBL23007878 | 0.89 | TGFBR1 (0.35) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993870-B | Imidazo pyrimidine compound containing fused ring group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-113993870-A | Imidazo pyrimidine compound containing polycyclic group, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-01-28 | — | — | CN | disclosed |