Pseudolaric Acid B

Pseudolaric Acid B

SCHEMBL29367226

COC(=O)C1=CC[C@@]23CCC(C(C)(/C=C/C=C(\C)C(=O)O)OC2=O)[C@@]3(OC(C)=O)CC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BSG P35613 1/20 0.58
CRBN Q96SW2 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pseudolaric Acid B SCHEMBL16426061 1.00 BSG (0.58) BSGCRBN
Pseudolaric Acid B SCHEMBL29357444 1.00 BSG (0.58) BSGCRBN
Pseudolaric Acid A SCHEMBL27964349 0.88 BSG (0.47) BSGCRBN
Pseudolaric Acid A SCHEMBL29785336 0.88 BSG (0.47) BSGCRBN
Pseudolaric Acid C SCHEMBL28774868 0.87 BSG (0.46) BSGCRBN
Pseudolaric Acid C SCHEMBL29754805 0.87 BSG (0.46) BSGCRBN
SCHEMBL28845305 0.86 BSG (0.45) BSGCRBN
SCHEMBL18561099 0.77 BSG (0.47) BSGCRBN
SCHEMBL16429224 0.74 BSG (0.37) BSGCRBN
SCHEMBL8255709 0.57 CHRM3 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325717-A1 ANTI-NUCLEOPHOSMIN 1 ANTIBODY AND ANTIBODY CONJUGATE COMBINATION THERAPIES THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-23 US claimed
US-20250313647-A1 MUTANT AND MISLOCALIZED CELL SURFACE NUCLEOPHOSMIN 1 AS A DIAGNOSTIC AND THERAPEUTIC TARGET OF HUMAN DISEASE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-09 US claimed
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-04-24 US claimed
CN-119677779-A Combination therapy with anti-nucleolin 1 antibodies and antibody conjugates 儿童医学中心公司 2025-03-21 CN claimed
EP-4514858-A2 MUTANT AND MISLOCALIZED CELL SURFACE NUCLEOPHOSMIN 1 AS A DIAGNOSTIC AND THERAPEUTIC TARGET OF HUMAN DISEASE The Children's Medical Center Corporation (US) 2025-03-05 EP claimed
EP-4514857-A2 ANTI-NUCLEOPHOSMIN 1 ANTIBODY AND ANTIBODY CONJUGATE COMBINATION THERAPIES The Children's Medical Center Corporation (US) 2025-03-05 EP claimed
CN-119487077-A Mutant and mislocalized cell surface nucleolin 1 as diagnostic and therapeutic targets for human diseases 儿童医学中心公司 2025-02-18 CN claimed
CN-119365486-A EPO receptor agonists and antagonists 免疫先锋股份有限公司 2025-01-24 CN claimed
EP-4490187-A2 EPO RECEPTOR AGONISTS AND ANTAGONISTS Immunedge, Inc. (US) 2025-01-15 EP claimed
CN-119112876-A Application of pseudolaric acid B in preparing medicine for preventing or treating non-alcoholic fatty liver disease 大连医科大学 2024-12-13 CN claimed
CN-115869244-A Anti-inflammatory and nursing liposome temperature-sensitive gel for vagina and preparation method thereof 广州金天芳颜化妆品有限公司 2023-03-31 CN claimed
US-20230012268-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2023-01-12 US claimed
CN-115252602-A Application of pseudolaric acid B in pharmacodynamic research of antitumor drugs 吉林大学 2022-11-01 CN claimed
EP-4072558-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR Buzzelet Development And Technologies Ltd (IL) 2022-10-19 EP claimed
CN-114794116-A Pesticide composition containing pseudolaric acid B and application thereof in preventing and treating plant diseases 兰州大学 2022-07-29 CN claimed
CN-113244225-B Application of pseudolaric acid B in preparation of antiplatelet drugs 昆明医科大学第一附属医院 2022-06-28 CN claimed
CN-114668757-A Application of pseudolaric acid B in preparing medicine for preventing and/or treating malignant tumor 葛鹏飞 2022-06-28 CN claimed
CN-113133964-B Multifunctional nail polish and preparation method thereof 浙江珍珠生活科技有限公司 2022-06-14 CN claimed
WO-2022056021-A1 METHODS OF DETECTING AN INACTIVATING MUTATION OF PBRM1 IN MENINGIOMA FOUNDATION MEDICINE, INC. (US) 2022-03-17 WO claimed
CN-113995749-A Application of pseudolaric acid B in preparing medicine for treating pulmonary hypertension 大连医科大学 2022-02-01 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS EPOR, MPL, PRLHR BSG 1131/4885CRBN 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.