Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 10/20 | 0.48 |
| ▸ | KDM5C | P41229 | 8/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.48 |
| ▸ | KDM6B | O15054 | 6/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.48 |
| ▸ | KDM4A | O75164 | 4/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678979 | 1.00 | CAMK2D (0.51) | CAMK2DLCKJAK3CDK2AURKA | |
| SCHEMBL29371192 | 0.99 | LCK (0.53) | CAMK2DLCKJAK3CDK2AURKA | |
| SCHEMBL28697590 | 0.99 | LCK (0.53) | CAMK2DLCKJAK3CDK2AURKA | |
| SCHEMBL28696318 | 0.89 | CDK2 (0.50) | LCKJAK3CDK2AURKAKDM2A | |
| SCHEMBL29371220 | 0.89 | CDK2 (0.50) | LCKJAK3CDK2AURKAKDM2A | |
| SCHEMBL28679844 | 0.88 | CDK2 (0.49) | LCKJAK3CDK2AURKAKDM2A | |
| SCHEMBL29371452 | 0.88 | CDK2 (0.49) | LCKJAK3CDK2AURKAKDM2A | |
| SCHEMBL29005369 | 0.85 | CDK2 (0.49) | CAMK2DJAK3CDK2KDM2AKDM5C | |
| SCHEMBL28674245 | 0.82 | IKBKB (0.54) | CDK2GSK3BIKBKBCHUKJAK2 | |
| SCHEMBL29368330 | 0.82 | IKBKB (0.54) | CDK2GSK3BIKBKBCHUKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999210-B | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2023-05-23 | — | — | CN | disclosed |
| CN-113999210-A | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2022-02-01 | — | — | CN | disclosed |