Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.32 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.32 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672381 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1HPGDRAB9AAPOBEC3A | |
| SCHEMBL22823743 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1HPGDRAB9AAPOBEC3A | |
| SCHEMBL31324222 | 0.90 | MAOB (0.36) | SMN1; SMN2ARCTSBSLC1A1UGCG | |
| SCHEMBL28688897 | 0.88 | PPARA (0.37) | SMN1; SMN2NPC1HPGDRAB9AAPOBEC3A | |
| SCHEMBL22823975 | 0.88 | PPARA (0.37) | SMN1; SMN2NPC1HPGDRAB9AAPOBEC3A | |
| SCHEMBL29369333 | 0.88 | PPARA (0.37) | SMN1; SMN2NPC1HPGDRAB9AAPOBEC3A | |
| SCHEMBL22823736 | 0.85 | PTGER1 (0.40) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL28673201 | 0.85 | PTGER1 (0.40) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL29368013 | 0.85 | PTGER1 (0.40) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL22823744 | 0.81 | HMGCR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008012-B | Compounds for the treatment of neuromuscular disorders | NMD制药股份公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-3986852-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD Pharma A/S (DK) | 2022-04-27 | — | — | EP | disclosed |
| CN-114008012-A | Compounds for the treatment of neuromuscular disorders | NMD制药股份公司 | 2022-02-01 | — | — | CN | disclosed |