Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 11/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22824019 | 1.00 | PTGDR2 (0.46) | PTGDR2LRRK2PTGER1MAPTCYP2C9 | |
| SCHEMBL29602289 | 1.00 | PTGDR2 (0.46) | PTGDR2LRRK2PTGER1MAPTCYP2C9 | |
| SCHEMBL22823736 | 0.89 | PTGER1 (0.40) | LRRK2PTGER1SMN1; SMN2POLBLMNA | |
| SCHEMBL28673201 | 0.89 | PTGER1 (0.40) | LRRK2PTGER1SMN1; SMN2POLBLMNA | |
| SCHEMBL29368013 | 0.89 | PTGER1 (0.40) | LRRK2PTGER1SMN1; SMN2POLBLMNA | |
| SCHEMBL31324222 | 0.85 | MAOB (0.36) | LRRK2MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL22824017 | 0.81 | PTGDR2 (0.49) | PTGDR2LRRK2MAPTCYP2C9CYP2C19 | |
| SCHEMBL29367739 | 0.81 | PTGDR2 (0.49) | PTGDR2LRRK2MAPTCYP2C9CYP2C19 | |
| SCHEMBL29601837 | 0.81 | PTGDR2 (0.49) | PTGDR2LRRK2MAPTCYP2C9CYP2C19 | |
| SCHEMBL22824021 | 0.80 | PTGDR2 (0.52) | PTGDR2LRRK2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008012-B | Compounds for the treatment of neuromuscular disorders | NMD制药股份公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114008012-A | Compounds for the treatment of neuromuscular disorders | NMD制药股份公司 | 2022-02-01 | — | — | CN | disclosed |