SCHEMBL29370249

SCHEMBL29370249

Clc1cc(Cl)c(-c2c(Cl)cccc2Cl)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.55
MAPK1 P28482 1/20 0.55
CYP2A6 P11509 2/20 0.39
CYP1A2 P05177 1/20 0.39
TSHR P16473 2/20 0.38
LMNA P02545 1/20 0.38
FGFR1 P11362 2/20 0.37
SRC P12931 2/20 0.37
NR4A2 P43354 1/20 0.36
CES1 P23141 1/20 0.34
GRIA1 P42261 1/20 0.34
CACNG8 Q8WXS5 1/20 0.34
PDK2 Q15119 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453300 1.00 AHR (0.55) AHRMAPK1CYP2A6CYP1A2TSHR
SCHEMBL7906592 0.84 TSHR (0.46) AHRMAPK1TSHRLMNAMEN1
SCHEMBL7907219 0.80 HSP90AA1 (0.49) AHRMAPK1GRIA1CACNG8ALDH1A1
SCHEMBL4445023 0.78 AHR (0.61) AHRMAPK1TSHRCES1ALDH1A1
SCHEMBL29434906 0.78 AHR (0.61) AHRMAPK1TSHRCES1ALDH1A1
SCHEMBL4450440 0.77 AHR (0.52) AHRMAPK1TSHRCES1ALDH1A1
SCHEMBL29455135 0.77 AHR (0.52) AHRMAPK1TSHRCES1ALDH1A1
SCHEMBL4453603 0.75 AHR (0.50) AHRMAPK1TSHRLMNAALDH1A1
SCHEMBL4459297 0.75 AHR (0.50) AHRCYP2A6CYP1A2TSHRLMNA
SCHEMBL4450490 0.75 AHR (0.57) AHRMAPK1CYP2A6CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120138013-A Clostridium butyricum genetically engineered bacterium for producing 1, 3-propanediol, construction method and application 广州大学 2025-06-13 CN claimed
CN-111154683-B Optimized culture method of methylotrophic butanobacterium and application thereof 南京工业大学 2022-05-13 CN claimed
EP-4077359-B1 GENETICALLY MODIFIED CLOSTRIDIUM STRAINS AND USES THEREOF LIVINGMED BIOTECH S R L (BE) 2026-03-18 EP disclosed
EP-4689128-A1 NUCLEIC ACID MOLECULE AND METHODS Forge Genetics Ltd (GB) 2026-02-11 EP disclosed
EP-4689059-A1 MODIFIED CLOSTRIDIUM BACTERIA, GENETIC EDITING TOOL FOR THE PSOL PLASMID OF CLOSTRIDIUM BACTERIA AND USES THEREOF IFP Energies nouvelles (FR) 2026-02-11 EP disclosed
EP-4689058-A1 MODIFIED CLOSTRIDIUM BACTERIA CAPABLE OF PRODUCING PROPAN-2-OL, AND PREPARATION AND USES THEREOF IFP Energies nouvelles (FR) 2026-02-11 EP disclosed
US-12497635-B2 Means and methods for producing isobutene from acetyl-CoA GLOBAL BIOENERGIES (FR) 2025-12-16 US disclosed
WO-2025247976-A1 ENGINEERED CRYPTIC PLASMIDS FROM C. BUTYRICUM UNIVERSITEIT MAASTRICHT (NL) 2025-12-04 WO disclosed
US-12472245-B2 Compositions and methods CHAIN BIOTECHNOLOGY LIMITED (GB) 2025-11-18 US disclosed
US-20250213673-A1 COMPOSITIONS AND METHODS CHAIN BIOTECHNOLOGY LIMITED (GB) 2025-07-03 US disclosed
CN-120138013-A Clostridium butyricum genetically engineered bacterium for producing 1, 3-propanediol, construction method and application 广州大学 2025-06-13 CN disclosed
CN-111154683-B Optimized culture method of methylotrophic butanobacterium and application thereof 南京工业大学 2022-05-13 CN disclosed
US-20220145336-A1 MEANS AND METHODS FOR PRODUCING ISOBUTENE FROM ACETYL-COA GLOBAL BIOENERGIES (FR) 2022-05-12 US disclosed
CN-114385024-A Method and system for detecting infrared touch module 青岛海信商用显示股份有限公司 2022-04-22 CN disclosed
CN-114341600-A Optical measurement device comprising an internal spectroscopic reference 唯亚威通讯技术有限公司 2022-04-12 CN disclosed
CN-216128156-U Vehicle-mounted charger and electric vehicle 华为数字能源技术有限公司 2022-03-25 CN disclosed
US-20220090096-A1 GENETIC CONSTRUCT UNIV NOTTINGHAM (GB) 2022-03-24 US disclosed
CN-114125255-A Camera module and electronic equipment 龙旗电子(惠州)有限公司 2022-03-01 CN disclosed
CN-110971388-B Method, device and equipment for communication between network equipment and remote equipment 华为技术有限公司 2022-02-18 CN disclosed
CN-215728421-U Direct current detection device 杨海河 2022-02-01 CN disclosed