SCHEMBL29370283

SCHEMBL29370283

O=C(O)c1ccccc1C(=O)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.71
KDM4E B2RXH2 1/20 0.69
MAPK1 P28482 1/20 0.58
CFTR P13569 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
ALDH1A1 P00352 3/20 0.54
ALOX15 P16050 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 2/20 0.51
MAPT P10636 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12172745 1.00 TSHR (0.71) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL9081047 0.87 TDP1 (0.59) TSHRKDM4ETDP1LPAR1
SCHEMBL9081531 0.87 TSHR (0.64) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL11901442 0.85 KDM4E (0.70) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL12354118 0.83 TSHR (1.00) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL31502347 0.82 KDM4E (0.60) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL31502409 0.82 KDM4E (0.60) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL946885 0.81 TSHR (0.67) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL3456433 0.81 TDP1 (0.70) TSHRKDM4EMAPK1CFTRTDP1
SCHEMBL4066112 0.81 TP53 (0.55) TSHRKDM4EMAPK1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4217412-A1 WASTE MITIGATION METHODS AND MATERIALS Finite Research Ltd (GB) 2023-08-02 EP disclosed
CN-115353667-A Method and material for reducing waste 李蓁蓁 2022-11-18 CN disclosed
WO-2022023916-A1 WASTE MITIGATION METHODS AND MATERIALS LI, Zhenzhen (CN) 2022-02-03 WO disclosed