Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.41 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291636 | 1.00 | CRBN (0.44) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL29367303 | 0.91 | CRBN (0.42) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL22291652 | 0.91 | CRBN (0.42) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL31736587 | 0.87 | IKZF2 (0.42) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL31736939 | 0.87 | IKZF2 (0.42) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL20233690 | 0.82 | CRBN (0.54) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL20133101 | 0.82 | CRBN (0.62) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL22291619 | 0.81 | DDB1 (0.55) | CRBNDDB1IKZF2IKZF1 | |
| SCHEMBL24185741 | 0.81 | CRBN (0.48) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL22737163 | 0.81 | CRBN (0.48) | CRBNDDB1ALDH1A1CHRM2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322780-A | Compounds and uses thereof | 福宏治疗公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4188447-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022025880-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-02-03 | — | — | WO | disclosed |