SCHEMBL31736587

SCHEMBL31736587

C[C@@H]1c2cc(C3CCNCC3)ccc2C(=O)N1[C@H]1CCC(=O)NC1=O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 7/20 0.42
▸ CRBN Q96SW2 12/20 0.42
▸ DDB1 Q16531 7/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ CHRM2 P08172 1/20 0.41
▸ OPRM1 P35372 1/20 0.41
▸ IKZF3 Q9UKT9 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31736939 1.00 IKZF2 (0.42) IKZF2CRBNDDB1ALDH1A1CHRM2
SCHEMBL29370547 0.87 CRBN (0.44) IKZF2CRBNDDB1ALDH1A1CHRM2
SCHEMBL22291636 0.87 CRBN (0.44) IKZF2CRBNDDB1ALDH1A1CHRM2
SCHEMBL27283251 0.83 CRBN (0.41) IKZF2CRBNDDB1ALDH1A1CHRM2
SCHEMBL30431923 0.82 CRBN (0.54) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL20046282 0.82 CRBN (0.54) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL30930626 0.82 CRBN (0.47) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL27267015 0.82 CRBN (0.47) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL26103591 0.81 CRBN (0.60) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL29367303 0.80 CRBN (0.42) IKZF2CRBNDDB1ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245178-A1 PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS INNOVO THERAPEUTICS, INC. (US) 2025-11-27 — — WO disclosed
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