Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 15/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16419630 | 1.00 | PDCD1LG2 (0.44) | PDCD1LG2CD274ALDH1A1GFERTUBB4A | |
| Hydrochloric Acid SCHEMBL28949992 | 0.98 | PDCD1LG2 (0.43) | PDCD1LG2CD274ALDH1A1GFERTUBB4A | |
| SCHEMBL19237079 | 0.84 | PDCD1LG2 (0.44) | PDCD1LG2CD274ALDH1A1TUBB4ATUBB | |
| SCHEMBL29599024 | 0.82 | PDCD1LG2 (0.43) | PDCD1LG2CD274ALDH1A1TUBB4ATUBB | |
| SCHEMBL17781570 | 0.82 | PDCD1LG2 (0.43) | PDCD1LG2CD274ALDH1A1TUBB4ATUBB | |
| SCHEMBL1848182 | 0.80 | POLB (0.46) | PDCD1LG2CD274ALDH1A1GFER | |
| SCHEMBL5781489 | 0.80 | APOBEC3A (0.44) | PDCD1LG2CD274ALDH1A1GFER | |
| SCHEMBL6962543 | 0.79 | CD274 (0.45) | PDCD1LG2CD274TUBB4ATUBBTUBA3C | |
| SCHEMBL6955607 | 0.79 | CD274 (0.48) | PDCD1LG2CD274TUBB4ATUBBTUBA3C | |
| SCHEMBL30028985 | 0.78 | PDCD1LG2 (0.36) | PDCD1LG2CD274ALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026081-B | Pyridone derivatives as selective cytotoxic agents against HIV-infected cells | 默沙东有限责任公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4232431-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | Lhotse Bio, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116583501-A | Compounds and compositions for treating conditions associated with LPA receptor activity | 罗特斯生物公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2022083703-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LHOTSE BIO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-114026081-A | Pyridone derivatives as selective cytotoxic agents against HIV-infected cells | 默沙东公司 | 2022-02-08 | — | — | CN | disclosed |