Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 12/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | CCR4 | P51679 | 6/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275212 | 0.82 | GABRA1 (0.35) | PDCD1LG2CD274CCR4CCR5 | |
| SCHEMBL1848182 | 0.82 | POLB (0.46) | PDCD1LG2CD274ALDH1A1GFERMAPT | |
| SCHEMBL29555593 | 0.81 | CD274 (0.40) | PDCD1LG2CD274ALDH1A1 | |
| SCHEMBL22690952 | 0.81 | CD274 (0.40) | PDCD1LG2CD274ALDH1A1 | |
| SCHEMBL29370691 | 0.78 | PDCD1LG2 (0.44) | PDCD1LG2CD274ALDH1A1GFER | |
| SCHEMBL5781489 | 0.78 | APOBEC3A (0.44) | PDCD1LG2CD274ALDH1A1GFERCCR5 | |
| SCHEMBL16419630 | 0.78 | PDCD1LG2 (0.44) | PDCD1LG2CD274ALDH1A1GFER | |
| Hydrochloric Acid SCHEMBL28949992 | 0.77 | PDCD1LG2 (0.43) | PDCD1LG2CD274ALDH1A1GFER | |
| SCHEMBL22690173 | 0.76 | S1PR4 (0.38) | PDCD1LG2CD274ALDH1A1GFERLMNA | |
| SCHEMBL2416576 | 0.74 | CCR4 (0.41) | ALDH1A1CCR4CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271674-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-08 | — | — | EP | disclosed |
| EP-4271672-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022225914-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022225941-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-27 | — | — | WO | disclosed |