SCHEMBL29371111

SCHEMBL29371111

CCOCC(=O)NC(C)(C)Cn1c(COCC)nc2c(N)nc3ccccc3c21

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.71
TLR8 Q9NR97 15/20 0.71
NUDT1 P36639 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3863883 1.00 TLR7 (0.71) TLR7TLR8NUDT1
SCHEMBL4129145 0.91 TLR7 (0.69) TLR7TLR8NUDT1
SCHEMBL4705732 0.90 TLR7 (0.67) TLR7TLR8NUDT1
SCHEMBL1042379 0.88 TLR7 (0.70) TLR7TLR8NUDT1
SCHEMBL4125001 0.88 TLR7 (0.67) TLR7TLR8NUDT1
SCHEMBL18204188 0.88 TLR7 (0.69) TLR7TLR8NUDT1
SCHEMBL22341400 0.87 TLR7 (0.55) TLR7TLR8NUDT1
SCHEMBL23255722 0.87 TLR7 (0.66) TLR7TLR8NUDT1
Hydrochloric Acid SCHEMBL4134550 0.87 TLR7 (0.66) TLR7TLR8NUDT1
SCHEMBL2744557 0.87 TLR7 (0.68) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4148069-A1 ANTI-PD-L1 CONJUGATES FOR TREATING TUMORS Birdie Biopharmaceuticals Inc. (KY) 2023-03-15 EP claimed
EP-3763742-B1 ANTI-PD-L1 CONJUGATES FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS INC (KY) 2022-10-05 EP claimed
CN-114716555-A Compounds and compositions for targeting EGFR expressing tumors 博笛生物科技有限公司 2022-07-08 CN claimed
CN-114671954-A Compounds and compositions targeting HER2 positive tumors 博笛生物科技有限公司 2022-06-28 CN claimed
EP-4001311-A1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS Birdie Biopharmaceuticals Inc. (KY) 2022-05-25 EP claimed
US-20260049145-A1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS INC (KY) 2026-02-19 US disclosed
EP-4691562-A2 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS Birdie Biopharmaceuticals Inc. (KY) 2026-02-11 EP disclosed
EP-4001311-B1 ANTI-PD-L1/PD-1 COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS INC (KY) 2025-11-05 EP disclosed
US-20250122304-A1 PRE-TARGETING PRECIRIX N.V. (BE) 2025-04-17 US disclosed
CN-119584994-A Pre-targeting 普雷西里克斯公司 2025-03-07 CN disclosed
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-12-07 US disclosed
WO-2023213801-A1 PRE-TARGETING PRECIRIX N.V. (BE) 2023-11-09 WO disclosed
CN-114671954-A Compounds and compositions targeting HER2 positive tumors 博笛生物科技有限公司 2022-06-28 CN disclosed
US-20220175762-A1 IMMUNE MODULATORY COMPOSITIONS AND METHODS FOR TREATING CANCERS BIRDIE BIOPHARMACEUTICALS INC (KY) 2022-06-09 US disclosed
EP-4001311-A1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS Birdie Biopharmaceuticals Inc. (KY) 2022-05-25 EP disclosed
US-20220089749-A1 ANTI-EGFR COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2022-03-24 US disclosed
US-11279761-B2 Anti-PD-L1 combinations for treating tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2022-03-22 US disclosed
WO-2022053651-A2 ANTIBODY FRAGMENT AGAINST FAP PRECIRIX N.V. (BE) 2022-03-17 WO disclosed
EP-3166976-B1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS INC (KY) 2022-02-23 EP disclosed
US-20220033503-A1 Anti PD-L1 Conjugates for Treating Tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049145-A1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS PDCD1, PDCD1LG2, CD274 TLR7 57/4885TLR8 90/4885NUDT1 4361/4885
US-11279761-B2 Anti-PD-L1 combinations for treating tumors PDCD1LG2, CD274, PDCD1 TLR7 879/4885TLR8 585/4885NUDT1 3947/4885
US-20220033503-A1 Anti PD-L1 Conjugates for Treating Tumors CD274, PDCD1LG2, PDCD1 TLR7 883/4885TLR8 671/4885NUDT1 4325/4885
US-20220175762-A1 IMMUNE MODULATORY COMPOSITIONS AND METHODS FOR TREATING CANCERS IFNG, CD47, CD74 TLR7 75/4885TLR8 61/4885NUDT1 3300/4885
US-20250122304-A1 PRE-TARGETING HNRNPH1, NR1H4, HNRNPH3 TLR7 2062/4885TLR8 3196/4885NUDT1 2674/4885
US-20220089749-A1 ANTI-EGFR COMBINATIONS FOR TREATING TUMORS EGFR, ERBB3, ERBB2 TLR7 2007/4885TLR8 1153/4885NUDT1 3504/4885
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885NUDT1 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.