SCHEMBL29373391

SCHEMBL29373391

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)N[C@@H](Cc1cnc[nH]1)C(=O)O)[C@@H](C)O)[C@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O)C(C)C

nearest known ligand 0.72

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 17/20 0.72
▸ ECE1 P42892 1/20 0.71
▸ MUS81 Q96NY9 1/20 0.71
▸ CCKBR P32239 1/20 0.70
▸ NR3C1 P04150 3/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350003 0.95 GLP1R (0.78) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29546813 0.91 GLP1R (0.75) GLP1RECE1MUS81CCKBR
SCHEMBL30683162 0.90 GLP1R (0.81) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29360422 0.89 GLP1R (0.88) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29370432 0.89 GLP1R (0.84) GLP1R
SCHEMBL31578362 0.89 GLP1R (0.73) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL31060658 0.89 GLP1R (0.89) GLP1RECE1MUS81CCKBRNR3C1
Glp-1 SCHEMBL29353361 0.89 GLP1R (0.89) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL31104924 0.88 GLP1R (0.66) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29395456 0.88 GLP1R (0.78) GLP1RECE1MUS81CCKBRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250236656-A1 MULTIMERIC POLYPEPTIDES AND USES THEREOF Amide Technologies (US) 2025-07-24 — — US claimed
EP-4582441-A2 MULTIMERIC POLYPEPTIDES AND USES THEREOF Amide Technologies (US) 2025-07-09 — — EP claimed
US-20250122239-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2025-04-17 — — US claimed
CN-119775356-A Preparation method of GLP-1 or analogue thereof 汉肽生物医药集团有限公司 2025-04-08 — — CN claimed
US-20240261421-A1 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING ANTAGONISTIC BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR)/GLP-1 RECEPTOR AGONIST FUSION PROTEINS AMGEN INC. (US) 2024-08-08 — — US claimed
EP-3891176-B1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2024-06-05 — — EP claimed
US-20230183309-A1 STRUCTURALLY-STABILIZED GLUCAGON-LIKE PEPTIDE 1 PEPTIDES AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. 2023-06-15 — — US claimed
EP-4077366-A1 STRUCTURALLY-STABILIZED GLUCAGON-LIKE PEPTIDE 1 PEPTIDES AND USES THEREOF Dana Farber Cancer Institute, Inc. (US) 2022-10-26 — — EP claimed
US-20220056077-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE RATNER, Cecilia (DK) 2022-02-24 — — US claimed
US-12636250-B2 Microneedle array patches (MAPs), systems, and methods for manufacturing and using same TERRESTRIAL BIO, INC. (US) 2026-05-26 — — US disclosed
CN-122081402-A Method for preparing semaglutin by using circRNA and related composition — 2026-05-26 — — CN disclosed
US-12630600-B2 GLP-1 and glucagon dual agonist peptides with improved biological stability MEDIMMUNE LIMITED (GB) 2026-05-19 — — US disclosed
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 — — CN disclosed
WO-2026098581-A1 PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR 深圳奥礼生物科技有限公司 2026-05-15 — — WO disclosed
CN-114126639-A Pharmaceutical compositions of glucagon and GLP-1 co-agonist peptides 免疫医疗有限公司 2022-03-01 — — CN disclosed
US-20220056077-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE RATNER, Cecilia (DK) 2022-02-24 — — US disclosed
US-11248037-B2 Multivalent heteromultimer scaffold design and constructs ZYMEWORKS INC. (CA) 2022-02-15 — — US disclosed
EP-3946261-A1 IONIC LIQUIDS FOR DRUG DELIVERY President And Fellows Of Harvard College (US) 2022-02-09 — — EP disclosed
US-20220033457-A1 TREATMENT OF NEUROLOGICAL DISEASES UNIVERSITY OF LANCASTER (GB) 2022-02-03 — — US disclosed
US-11230584-B2 Glucagon/GLP-1 agonists for the treatment of obesity MEDIMMUNE LIMITED (GB) 2022-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183309-A1 STRUCTURALLY-STABILIZED GLUCAGON-LIKE PEPTIDE 1 PEPTIDES AND USES THEREOF GLP1R, IAPP, GPR119 GLP1R 1/4885ECE1 2947/4885MUS81 3965/4885
US-12630600-B2 GLP-1 and glucagon dual agonist peptides with improved biological stability GLP1R, GIPR, GCGR GLP1R 1/4885ECE1 373/4885MUS81 4365/4885
US-12636250-B2 Microneedle array patches (MAPs), systems, and methods for manufacturing and using same GLP1R, NPY1R, NPY4R GLP1R 1/4885ECE1 4125/4885MUS81 4876/4885
US-20250236656-A1 MULTIMERIC POLYPEPTIDES AND USES THEREOF GIPR, GRPR, SCTR GLP1R 5/4885ECE1 894/4885MUS81 4265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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