Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3737888 | 0.91 | IGF1R (0.68) | IGF1R | |
| SCHEMBL2937078 | 0.87 | IGF1R (0.75) | IGF1RTAS2R8 | |
| SCHEMBL2935389 | 0.84 | IGF1R (0.56) | IGF1RTAS2R8 | |
| SCHEMBL1130587 | 0.83 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4888208 | 0.83 | IGF1R (0.72) | IGF1RTAS2R8 | |
| SCHEMBL4881565 | 0.81 | IGF1R (0.61) | IGF1RTAS2R8 | |
| SCHEMBL13039129 | 0.81 | IGF1R (0.67) | IGF1RTAS2R8 | |
| SCHEMBL13039186 | 0.80 | IGF1R (0.68) | IGF1RTAS2R8 | |
| SCHEMBL2940459 | 0.79 | IGF1R (0.64) | IGF1RTAS2R8 | |
| SCHEMBL4891050 | 0.79 | IGF1R (0.64) | IGF1RTAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |