SCHEMBL29373534

SCHEMBL29373534

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 19/20 0.66
▸ NPY1R P25929 12/20 0.66
▸ NPY5R Q15761 10/20 0.66
▸ NPY2R P49146 8/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376626 0.99 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30385910 0.94 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30386233 0.94 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30334190 0.94 NPY4R (0.73) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30153268 0.93 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31679394 0.93 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30731371 0.92 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL13563452 0.92 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL18951657 0.92 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30688833 0.92 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015399-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 — — US claimed
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 — — EP claimed
CN-116171282-A Soluble NPY2 receptor agonists 勃林格殷格翰国际有限公司 2023-05-26 — — CN claimed
US-20220041678-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — US claimed
WO-2022029231-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — WO claimed
CN-122071508-A Targeting NPY polypeptide nuclide ligand and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-22 — — CN disclosed
US-20260015399-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 — — US disclosed
US-12391737-B2 Soluble NPY2 receptor agonists BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-08-19 — — US disclosed
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 — — EP disclosed
CN-116171282-A Soluble NPY2 receptor agonists 勃林格殷格翰国际有限公司 2023-05-26 — — CN disclosed
US-20220041678-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — US disclosed
WO-2022029231-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041678-A1 SOLUBLE NPY2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R NPY4R 4/4885NPY1R 2/4885NPY5R 3/4885
US-12391737-B2 Soluble NPY2 receptor agonists NPY2R, NPY1R, NPY5R NPY4R 4/4885NPY1R 2/4885NPY5R 3/4885
US-20260015399-A1 SOLUBLE NPY2 RECEPTOR AGONISTS NPY1R, NPY2R, NPY5R NPY4R 4/4885NPY1R 1/4885NPY5R 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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