Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2937402 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3098025 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL8622638 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7923575 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL7923574 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL2937378 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL2937379 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL3688980 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL3688981 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL3682267 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316560-B1 | COPOLYMERIZING POLYCYCLIC OLEFIN, MONOCYCLIC OLEIN AND ACYCLIC 1-OLEFIN IN PRESENCE OF METALLOCENE CATALYST AND COCATALYST | TICONA GMBH (DE) | 2001-11-13 | — | — | US | claimed |
| US-7816450-B2 | Transparent thermoplastic blend of a cycloolefin copolymer and a thermoplastic polyurethane | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| EP-1664185-B1 | A TRANSPARENT THERMOPLASTIC BLEND OF A CYCLOOLEFIN COPOLYMER AND A THERMOPLASTIC POLYURETHANE | LUBRIZOL ADVANCED MAT INC (US) | 2010-09-15 | — | — | EP | disclosed |
| US-20090143533-A1 | Transparent Thermoplastic Blend Of A Cycloolefin Copolymer And A Thermoplastic Polyurethane | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2009-06-04 | — | — | US | disclosed |
| EP-1664185-A1 | A TRANSPARENT THERMOPLASTIC BLEND OF A CYCLOOLEFIN COPOLYMER AND A THERMOPLASTIC POLYURETHANE | Noveon IP Holdings Corp. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005030861-A1 | A TRANSPARENT THERMOPLASTIC BLEND OF A CYCLOOLEFIN COPOLYMER AND A THERMOPLASTIC POLYURETHANE | NOVEON IP HOLDINGS CORP. (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070665-A1 | Transparent thermoplastic blend of a cycloolefin copolymer and a thermoplastic polyurethane | LUBRIZOL ADVANCED MATERIALS, INC. | 2005-03-31 | — | — | US | disclosed |
| US-6316560-B1 | COPOLYMERIZING POLYCYCLIC OLEFIN, MONOCYCLIC OLEIN AND ACYCLIC 1-OLEFIN IN PRESENCE OF METALLOCENE CATALYST AND COCATALYST | TICONA GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6225407-B1 | IMPACT-RESISTANT, FLEXURAL STRENGTH AND ELONGATION AT BREAK | TICONA GMBH (DE) | 2001-05-01 | — | — | US | disclosed |