SCHEMBL29374829

SCHEMBL29374829

CC(C)(C)OC(=O)CC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 6/20 0.55
TLR2 O60603 2/20 0.54
MDM4 O15151 2/20 0.53
TP53 P04637 2/20 0.53
CASP3 P42574 1/20 0.49
SLC17A5 Q9NRA2 1/20 0.48
TNF P01375 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29792372 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
SCHEMBL178744 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
SCHEMBL30649315 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
SCHEMBL29352017 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
SCHEMBL29768913 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
SCHEMBL29792120 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
SCHEMBL117964 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
SCHEMBL120511 1.00 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
Water SCHEMBL22070159 0.99 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3
Water SCHEMBL31472478 0.99 MDM2 (0.55) MDM2TLR2MDM4TP53CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098617-A1 RADIOPHARMACEUTICAL TARGETING CARBONIC ANHYDRASE IX PROTEIN 无锡诺宇医药科技有限公司 2026-05-15 WO disclosed
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS NORROY BIOSCIENCE CO LTD (CN) 2026-05-14 US disclosed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 US disclosed
EP-4720097-A1 PEPTIDES WITH LIPOLYTIC, ANTI-LIPOGENIC, ANTIFIBROTIC AND ANTI-INFLAMMATORY ACTIVITY Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (ES) 2026-04-08 EP disclosed
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 US disclosed
US-12569577-B2 PSMA-targeting imaging agents THE CLEVELAND CLINIC FOUNDATION (US) 2026-03-10 US disclosed
US-20260049102-A1 A PRO-MOIETY FOR FORMING A PRODRUG SELECTIVELY CLEAVED BY PROSTATE-SPECIFIC ANTIGEN (PSA) UNIV SYDNEY (AU) 2026-02-19 US disclosed
EP-4696680-A1 DUAL-FUNCTIONAL TETRAZINE COMPOUNDS FOR VERSATILE RADIOLABELING WITH RADIOMETALS AND RADIOHALOGENS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS Tetrakit Technologies ApS (DK) 2026-02-18 EP disclosed
US-20260015389-A1 V1A Receptor Partial Agonist and Method of Use PHARMALN CORP (US) 2026-01-15 US disclosed
CN-114380886-A Tumor targeting polypeptide, polypeptide conjugate drug and application thereof 深圳深创生物药业有限公司 2022-04-22 CN disclosed
CN-114364690-A Novel radiolabeled CXCR4 targeting compounds for diagnosis and therapy 省卫生服务机构 2022-04-15 CN disclosed
WO-2022075974-A1 CYCLIC TREX1 INHIBITORS Venenum Biodesign, LLC (US) 2022-04-14 WO disclosed
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2022-03-31 US disclosed
EP-3973990-A1 PROMOTOR FOR PERMEATION INTO CELL LAYER, COMPOSITION FOR FACILITATING DRUG AGENT ABSORPTION, AND PHARMACEUTICAL COMPOSITION University of Tsukuba (JP) 2022-03-30 EP disclosed
EP-3966234-A1 VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF Consejo Superior De Investigaciones Científicas (ES) 2022-03-16 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-3956346-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY Provincial Health Services Authority (CA) 2022-02-23 EP disclosed
US-20220040231-A1 COMBINATION THERAPY OF ARMS AND NATURAL KILLER CELLS BIOHAVEN THERAPEUTICS LTD. 2022-02-10 US disclosed
EP-3946320-A1 HSP90-BINDING CONJUGATES AND FORMULATIONS THEREOF Tarveda Therapeutics, Inc. (US) 2022-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569577-B2 PSMA-targeting imaging agents FOLH1, PSMA2, PSMA1 MDM2 3378/4885TLR2 3156/4885MDM4 3551/4885
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS CA9, CA11, CA12 MDM2 4177/4885TLR2 4443/4885MDM4 4599/4885
US-20260015389-A1 V1A Receptor Partial Agonist and Method of Use AVPR1A, AVPR1B, AVPR2 MDM2 4848/4885TLR2 1192/4885MDM4 4621/4885
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF FOLH1, KLK3, FRS2 MDM2 3205/4885TLR2 3488/4885MDM4 3612/4885
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR MDM2 1864/4885TLR2 729/4885MDM4 4874/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 MDM2 3597/4885TLR2 489/4885MDM4 3817/4885
US-20260049102-A1 A PRO-MOIETY FOR FORMING A PRODRUG SELECTIVELY CLEAVED BY PROSTATE-SPECIFIC ANTIGEN (PSA) FOLH1, PSAP, KLK3 MDM2 4183/4885TLR2 4628/4885MDM4 3782/4885
US-20220040231-A1 COMBINATION THERAPY OF ARMS AND NATURAL KILLER CELLS PBK, CD47, ICOS MDM2 1231/4885TLR2 158/4885MDM4 1292/4885
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof KLK3, FOLH1, SLC7A1 MDM2 3098/4885TLR2 1062/4885MDM4 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.