Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.69 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 5/20 | 0.48 |
| ▸ | KIT | P10721 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | BLK | P51451 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58763 | 1.00 | KDR (0.69) | KDRPDGFRBRAB9AMAPTNPC1 | |
| SCHEMBL59552 | 0.88 | KDR (0.58) | KDRPDGFRBRAB9AMAPTNPC1 | |
| SCHEMBL19067997 | 0.88 | PDGFRB (0.55) | KDRPDGFRBRAB9AMAPTNPC1 | |
| SCHEMBL12491398 | 0.86 | PDGFRB (0.56) | KDRPDGFRBRAB9AMAPTNPC1 | |
| SCHEMBL31212719 | 0.85 | KDR (0.61) | KDRPDGFRBFLT3KITCA1 | |
| SCHEMBL57825 | 0.85 | KDR (0.61) | KDRPDGFRBFLT3KITCA1 | |
| SCHEMBL424260 | 0.84 | KDR (0.55) | KDRPDGFRBRAB9AMAPTNPC1 | |
| SCHEMBL59133 | 0.84 | KDR (0.51) | KDRPDGFRBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL422410 | 0.84 | NPC1 (0.59) | KDRPDGFRBRAB9AMAPTNPC1 | |
| SCHEMBL17200537 | 0.84 | PDGFRB (0.50) | KDRPDGFRBRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022026380-A1 | UREA INHIBITORS OF MICRO-RNA | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-02-03 | — | — | WO | disclosed |