SCHEMBL29375652

SCHEMBL29375652

Brc1ccc(N2c3ccccc3Sc3ccccc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.58
BCHE P06276 7/20 0.53
MAOA P21397 1/20 0.47
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
ALOX12 P18054 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SLC6A3 Q01959 1/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
ACHE P22303 2/20 0.40
HPGD P15428 1/20 0.40
NOX1 Q9Y5S8 1/20 0.40
KDM1A O60341 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
PIM1 P11309 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1022593 1.00 HDAC6 (0.58) HDAC6BCHEMAOAMEN1MAPT
SCHEMBL23057479 0.94 HDAC6 (0.54) HDAC6BCHEMAOAMEN1MAPT
SCHEMBL29851224 0.89 HDAC6 (0.62) HDAC6BCHEMAOAMEN1KMT2A
SCHEMBL12190901 0.89 HDAC6 (0.62) HDAC6BCHEMAOAMEN1KMT2A
SCHEMBL24024212 0.86 HDAC6 (0.50) HDAC6BCHEMAOAMEN1MAPT
SCHEMBL28407558 0.84 HDAC6 (0.48) HDAC6BCHEMAOAMEN1MAPT
SCHEMBL15470433 0.84 HDAC6 (0.48) HDAC6BCHEMAOAMEN1MAPT
SCHEMBL15470447 0.83 HDAC6 (0.57) HDAC6BCHEMAOAMEN1KMT2A
SCHEMBL342426 0.83 HDAC6 (0.56) HDAC6BCHEMAOAMEN1KMT2A
SCHEMBL29387100 0.83 HDAC6 (0.56) HDAC6BCHEMAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899395-A Preparation method and application of copper cluster-phenothiazinyl metal organic framework with visible light catalytic C-N bond cross-coupling performance 大连理工大学 2025-04-29 CN claimed
EP-3806176-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2025-06-25 EP disclosed
CN-120058638-A Preparation method of phenothiazine derivative for generating singlet oxygen 合肥大学 2025-05-30 CN disclosed
CN-119899395-A Preparation method and application of copper cluster-phenothiazinyl metal organic framework with visible light catalytic C-N bond cross-coupling performance 大连理工大学 2025-04-29 CN disclosed
CN-113292514-B Piperazine derivative and organic photoelectric device comprising same 浙江华显光电科技有限公司 2022-11-15 CN disclosed
US-11245079-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11245079-B2 Materials for organic electroluminescent devices OR10J3, L1CAM, EPCAM HDAC6 4524/4885BCHE 658/4885MAOA 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.