⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608286 | 0.88 | QPCT (0.47) | — | |
| SCHEMBL10529956 | 0.82 | — | — | |
| SCHEMBL31251980 | 0.82 | QPCT (0.48) | — | |
| SCHEMBL1178918 | 0.78 | — | — | |
| SCHEMBL8604979 | 0.78 | — | — | |
| SCHEMBL24496205 | 0.78 | — | — | |
| SCHEMBL27850201 | 0.77 | — | — | |
| Bromide SCHEMBL6375209 | 0.77 | ALPL (0.41) | — | |
| SCHEMBL634200 | 0.77 | CYP1A2 (0.45) | — | |
| SCHEMBL28796556 | 0.76 | ALPL (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119461-A1 | STABILIZED POLYURETHANE POLYOL BLENDS CONTAINING HALOGENATED OLEFIN BLOWING AGENT | ARKEMA INC (US) | 2019-04-25 | — | — | US | claimed |
| US-20160130416-A1 | STABILIZED POLYURETHANE POLYOL BLENDS CONTAINING HALOGENATED OLEFIN BLOWING AGENT | ARKEMA INC. | 2016-05-12 | — | — | US | claimed |
| EP-3004226-A1 | STABILIZED POLYURETHANE POLYOL BLENDS CONTAINING HALOGENATED OLEFIN BLOWING AGENT | Arkema, Inc. (US) | 2016-04-13 | — | — | EP | claimed |
| CN-105264000-A | Stabilized polyurethane polyol blends containing halogenated olefin blowing agents | ARKEMA INC | 2016-01-20 | — | — | CN | claimed |
| WO-2014193689-A1 | STABILIZED POLYURETHANE POLYOL BLENDS CONTAINING HALOGENATED OLEFIN BLOWING AGENT | ARKEMA INC. (US) | 2014-12-04 | — | — | WO | claimed |
| WO-2009005460-A1 | SMALL MOLECULE INHIBITORS OF NAVL.7 SODIUM CHANNELS FOR THE TREATMENT OF PAIN DISORDERS | ASTRAZENECA AB (SE) | 2009-01-08 | — | — | WO | claimed |
| WO-2023159307-A1 | POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | REPARE THERAPEUTICS INC. (CA) | 2023-08-31 | — | — | WO | disclosed |
| US-20230064702-A1 | HIGH Tg ACRYLATE COPOLYMERS WITH NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP | TESA SE (DE) | 2023-03-02 | — | — | US | disclosed |
| CN-113896873-A | Branched polyester ionomer auxiliary agent constructed based on ionic bonds and preparation method and application thereof | 重庆文理学院 | 2022-01-07 | — | — | CN | disclosed |
| CN-105264000-B | Stabilized polyurethane polyol blends containing halogenated olefin blowing agents | 阿科玛股份有限公司 | 2021-04-27 | — | — | CN | disclosed |
| US-20190119461-A1 | STABILIZED POLYURETHANE POLYOL BLENDS CONTAINING HALOGENATED OLEFIN BLOWING AGENT | ARKEMA INC (US) | 2019-04-25 | — | — | US | disclosed |
| CN-108641515-A | High-adhesion primer coating | 湖南松井新材料股份有限公司 | 2018-10-12 | — | — | CN | disclosed |
| US-20160130416-A1 | STABILIZED POLYURETHANE POLYOL BLENDS CONTAINING HALOGENATED OLEFIN BLOWING AGENT | ARKEMA INC. | 2016-05-12 | — | — | US | disclosed |
| US-20080096914-A1 | Tetrahydropyridothiophenes for the Treatment of Proliferative Diseases Such as Cancer | ALTANA PHARMA AG (DE) | 2008-04-24 | — | — | US | disclosed |
| EP-1851230-A1 | TETRAHYDROPYRIDOTHIOPHENES AS ANTRIPOLIFERATIVE AGENTS FOR THE TREATMENT OF CANCER | Nycomed GmbH (DE) | 2007-11-07 | — | — | EP | disclosed |
| EP-1851229-A1 | TETRAHYDROPYRIDOTHIOPHENES FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER | Nycomed GmbH (DE) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006084904-A1 | TETRAHYDROPYRIDOTHIOPHENES AS ANTRIPOLIFERATIVE AGENTS FOR THE TREATMENT OF CANCER | NYCOMED GMBH (DE) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006084869-A1 | TETRAHYDROPYRIDOTHIOPHENES FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER | NYCOMED GMBH (DE) | 2006-08-17 | — | — | WO | disclosed |
| CN-1133625-C | Quinazoline derivatives | — | 2004-01-07 | — | — | CN | disclosed |
| CN-1205694-A | Quinazoline derivatives | ZENECA LTD (GB) | 1999-01-20 | — | — | CN | disclosed |