Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | GALR2 | O43603 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22463095 | 1.00 | MAPT (0.45) | MAPTNPSR1ALDH1A1HTTPKM | |
| SCHEMBL9868010 | 0.90 | NPSR1 (0.45) | MAPTNPSR1ALDH1A1HTTPKM | |
| SCHEMBL7652191 | 0.83 | BAZ2B (0.44) | MAPTNPSR1ALDH1A1POLBBAZ2B | |
| SCHEMBL7154811 | 0.82 | MAPT (0.50) | MAPTNPSR1ALDH1A1HTTPKM | |
| SCHEMBL22463098 | 0.78 | BAZ2B (0.40) | MAPTALDH1A1POLBBAZ2BHPGD | |
| SCHEMBL29375779 | 0.78 | BAZ2B (0.40) | MAPTALDH1A1POLBBAZ2BHPGD | |
| SCHEMBL7653325 | 0.77 | BRD4 (0.39) | MAPTALDH1A1HTTKMT2AHPGD | |
| SCHEMBL22463087 | 0.76 | BAZ2B (0.43) | MAPTNPSR1ALDH1A1HTTPOLB | |
| SCHEMBL10748451 | 0.76 | BAZ2B (0.46) | MAPTNPSR1ALDH1A1HTTKMT2A | |
| SCHEMBL31177224 | 0.76 | TP53 (0.53) | MAPTALDH1A1POLBKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946464-A1 | COMPOUNDS AND CONJUGATES THEREOF | MedImmune Limited (GB) | 2022-02-09 | — | — | EP | disclosed |