Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22463098 | 1.00 | BAZ2B (0.40) | BAZ2BMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL7652191 | 0.88 | BAZ2B (0.44) | BAZ2BMAPTBRD4NPC1ALDH1A1 | |
| SCHEMBL22519655 | 0.81 | BRD4 (0.40) | MAPTBRD4ALDH1A1HPGDKDM4E | |
| SCHEMBL25692600 | 0.81 | AAK1 (0.39) | MAPTBRD4ALDH1A1HPGDRAB9A | |
| SCHEMBL7653960 | 0.79 | BAZ2B (0.42) | BAZ2BMAPTBRD4NPC1ALDH1A1 | |
| SCHEMBL22463090 | 0.78 | L3MBTL1 (0.40) | BAZ2BMAPTBRD4ALDH1A1HPGD | |
| SCHEMBL22463095 | 0.78 | MAPT (0.45) | BAZ2BMAPTALDH1A1HPGDPOLB | |
| SCHEMBL29375798 | 0.78 | MAPT (0.45) | BAZ2BMAPTALDH1A1HPGDPOLB | |
| SCHEMBL29376104 | 0.78 | L3MBTL1 (0.40) | BAZ2BMAPTBRD4ALDH1A1HPGD | |
| SCHEMBL25692601 | 0.77 | BAZ2B (0.36) | BAZ2BMAPTBRD4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263948-B | Compounds and conjugates thereof | 免疫医疗有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118240003-A | Compounds and conjugates thereof | 免疫医疗有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118221763-A | Compounds and conjugates thereof | 免疫医疗有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-113631196-B | Compounds and conjugates thereof | 免疫医疗有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117263948-A | Compounds and conjugates thereof | 免疫医疗有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116829592-A | Therapeutic B7-H4 binding molecules | 免疫医疗有限公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-4211166-A1 | THERAPEUTIC B7-H4 BINDING MOLECULES | MedImmune Limited (GB) | 2023-07-19 | — | — | EP | disclosed |
| EP-4093439-A1 | COMPOUNDS AND CONJUGATES THEREOF | MedImmune Limited (GB) | 2022-11-30 | — | — | EP | disclosed |
| CN-114980934-A | Compounds and conjugates thereof | 免疫医疗有限公司 | 2022-08-30 | — | — | CN | disclosed |
| WO-2022053650-A1 | THERAPEUTIC B7-H4 BINDING MOLECULES | MEDIMMUNE LIMITED (GB) | 2022-03-17 | — | — | WO | disclosed |
| EP-3946464-A1 | COMPOUNDS AND CONJUGATES THEREOF | MedImmune Limited (GB) | 2022-02-09 | — | — | EP | disclosed |